In cell culture experiments, purified B cells expressing IgM can be induced to switch to producing IgE by stimulating them with an antibody to CD40 (a stimulatory antibody) plus the cytokine IL-4. In an individual undergoing an immune response, these signals would normally be provided by O follicular dendritic cells in the germinal center. Oother B cells in the germinal center. O TFH cells in the germinal center. Oany CD4 T cell in the same lymph node.

In cell culture experiments, purified B cells expressing IgM can be induced to switch to producing IgE by stimulating them with an antibody to CD40 (a stimulatory antibody) plus the cytokine IL-4. In an individual undergoing an immune response, these signals would normally be provided by O follicular dendritic cells in the germinal center. Oother B cells in the germinal center. O TFH cells in the germinal center. Oany CD4 T cell in the same lymph node.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter17: Genes And The Immune System

Section: Chapter Questions

Problem 31QP

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