Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Question 19
Cells undergoing viral infection upregulate the expression of the stress molecules MIC-A and MIC-B. One evasion strategy adopted by Hepatitis B virus is to
interfere with upregulation of these stress molecules by infected cells. This is advantageous to the virus because:
O MIC-A and MIC-B are recognized by inhibitory receptors on NK cells
NK cells upregulate activating receptors
O MIC-A and MIC-B are recognized by KIR receptors on NK cells
O Killing by NK cells is inhibited.
O NK cells perceive lack of MIC-A/MIC-B as missing-self
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