If a fragment of a chromosome breaks off and then reattaches to the original chromosome but in the reverse direction, the resulting chromosomal abnormality is called a translocation." The above statement is True or False? and Explain

If a fragment of a chromosome breaks off and then reattaches to the original chromosome but in the reverse direction, the resulting chromosomal abnormality is called a translocation." The above statement is True or False? and Explain

Name: "If a fragment of a chromosome breaks off and then reattaches to the o
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Description: "If a fragment of a chromosome breaks off and then reattaches to the original chromosome but in the reverse direction, the resulting chromosomal abnormality is called a translocation."The above statement is True or False? and Explain

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter20: Chromosomes And Human Genetics

Section: Chapter Questions

Problem 3CT: People with Down syndrome have an extra copy of chromosome 21, for a total of 47 chromosomes....

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Variations in Chromosome NumberAneuploidy Describe the process of nondisjunction and explain when it takes place during cell division.
A girl and a boy were born to a young married couple. The girl is absolutely healthy. The examination of the boy's karyotype has shown 46 chromosomes. But one of the chromosomes of the 15th pair is longer than normal as a part of a chromosome from the 21st pair has joined it. How many autosomes and sex chromosomes are in the boy's karyotype? Name the type of the mutation. Is it possible to consider this pathology an inherited disorder?
B. A woman is a carrier of a Robertsonian translocation between chromosomes 18 and 21. (i) Her chromosome set with respect to chromosomes 18 and 21 would consist of which specific chromosomes. Please draw a DIAGRAM illustrating these chromosomes as they would appear in their unreplicated state, clearly labeling the chromosomes and the chromosome arms present. (ii) If this woman were to have a child with a man who possess a completely normal set of chromosomes, there are six different possible outcomes with respect to the combinations of chromosomes 18, 21, and Robertsonian translocation chromosome that could be present in their offspring. Please indicate the TYPES and NUMBERS of chromosomes of each type present in their potential offspring. You may label the chromosomes as follows: 18 (for chromosome 18), 21 (for chromosome 21) or 18/21 (for the Robertsonian translocation chromosome). Also, please indicate the specific genetic abnormality (if any) that would be present in…
Chromosome Pairs 1-22 are considered what type of chromosomes?
A phenotypically normal individual has the following combinations of normal and abnormal chromosomes:The normal chromosomes are shown on the left in each pair.Suggest a series of events (breaks, translocations, crossovers, etc.)that may have produced this combination of chromosomes.
Familial Down syndrome is similar to primary Down syndrome in that it is caused by trisomy 21. However, in familial Down syndrome, all or part of the third copy of chromosome 21 has translocated onto another autosome, typically chromosome 14. In cases of familial Down syndrome, one of the parents of the affected child is often a carrier of a translocated chromosome. The translocation carrier parent does not have Down syndrome because he or she has a total of two copies of chromosome 21. Suppose that a woman is a translocation carrier of chromosome 21 on chromosome 14. She conceives six zygotes with a man who carries no aneuploidies. Match the description of the chromosomes inherited by each zygote with the viability and phenotype of the zygote. ✓ Two normal copies of 14, two normal copies of 21 two normal copies of 21, one normal copy of 14 ✓one normal copy of 14, one 21 to 14 translocation, one normal copy of 21 ✓two normal copies of 14, one normal copy of 21, on 21 to 14…
In humans, chromosome 16 sometimes has a heavily stained area near the centromere. This feature can be seen in a microscope, but otherwise has no effect on the phenotype of the person carrying it. When such a “blob" exists on a given copy of chromosome 16, it is a constant feature of that chromosome and is inherited. A couple conceived a child, but the fetus had multiple abnormalities and was miscarried. e.g., The fetus had three copies of chromosome 16, where 2 of the 3 copies of chromosome 16 had large blobs. Both of the mother's copies of chromosome 16 lacked blobs, but the father was heterozygous for blobs. The fetus was formed from a fertilization event that included a gamete produced by the in which nondisjunction occurred during the meiotic division. Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a mother; first. mother; second. father; first. C Your answer d father; second. E3 Fullso L e Insufficient information is provided…
Two phenotypically normal parents produce a phenotypically abnormal child in which chromosome 5 is missing part of its long arm but has a piece of chromosome 7 attached to it. The child also has one normal copy of chromosome 5 and two normal copies of chromosome 7. With regard to chromosomes 5 and 7, what do you think are the chromosomal compositions of the parents? Would it most likely be reciprocal translocation? It wouldn't be simple translocation because then the child would have the entirety of one chromosome and only some of the other, but in this case, there is only partial chromosome 5 and chromosome 7?
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describe a specific example of chromosome abnormality that leads to human cancers, such as leukemia, other than the Philadelphia chromosome that is derived from the translocation of chromosome 9 and 22
What type of chromosomal rearrangement occurs If a single chromosome suffers two double-strand breaks followed by DNA repair that fuses the remaining broken ends (nonhomologous end-joining) if the intervening fragment rotates by 180°?
In humans, chromosome 16 sometimes has a heavily stained area in the long arm near the centromere. This feature can be seen through the microscope but has no effect on the phenotype of the person carrying it. When such a “blob” exists on a particular copy of chromosome 16, it is a constant feature of that chromosome and is inherited. A couple conceived a child, but the fetus had multiple abnormalities and was miscarried. When the chromosomes of the fetus were studied, it was discovered that it had three copies of chromosome 16 (it was trisomic for chromosome 16), and that two of the three chromosome 16s had large blobs. Both chromosome 16 homologs in the mother lacked blobs, but the father was heterozygous for blobs. Which parent experienced nondisjunction, and in which meiotic division did it occur?