HCI RC=N + R'OH R the Ritter reaction NHR'

Q: 1. using curved arrows draw the mechanism to show the SN2 reaction of hydroxide ion with (R)…

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Q: 11 Show the best way to transform benzoic acid into benzamide. benzoic acid benzamide ----→

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Q: Draw the products formed when benzoyl chloride (C,H;COCI) is treated with each nucleophile: (a) H20,…

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Q: Consider the following reaction schemes involving the reaction of an imine with an organolithium…

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Q: 28. What reagent(s) will accomplish this conversion? (Et = ethyl) * EtMgBr followed by an acid wash…

A: 29.) First we would convert the Fischer projection to Haworth projection. Both the alcohol OH…

Q: An organic chemist reacts 1-butanol with SOCI2 in pyridine, removes the major organic product, and…

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Q: trans-stilbene trans-stilbene 2-bromo-1,2-diphenylethanol (a bromohydrin) Br 24 OH B. NBS C.DMSO…

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Q: Choose the most appropriate reagent(s) for conversion of ethyl acetate to acetamide. H OEt OCH2CH3 H…

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Q: GS Q1: Show the reactants needed to make the acetal below.

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Q: Synthesize the following compound from cyclohexanol using any other organic or inorganic compounds.…

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Q: In the Gabriel synthesis of primary amines, N-potassiophthalimide is used as a source of the…

A: This is a Gabriel phthalamide synthesis reaction. Through this reaction 1° amine is produced by the…

Q: The reaction of a nitrile with an alcohol in the presence of a strong acid forms an N-substituted…

A: Ritter reaction is the one in which the conversion of nitrile and a substituted precursor of the…

Q: 2. a) Why does benzene show electrophilic aromatic substitution rather than electrophilic aromatic…

A: Answer (a)  Benzene is a planar molecule. In a molecule of benzene molecule have delocalized…

Q: Which pathway is favored for the reaction of N2OCH3 with 1-bromonane? NaOCH3 Br A. SN1 B. SN2 С. Е2…

A: The reaction between 1-bromononane and NaOCH3 occurs as:

Q: f. propanoic anhydride g. cyclohexyl propanoate h. 3-methylhexanoyl chloride i.…

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Q: How is an amide converted to an anhydride? Water with strong acid → PCl5 → Carboxylic Acid PCl5 →…

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Q: A2. Which reagent should be paired with acetic anhydride to produce: ? A. В. C. D. OH OH OH

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Q: Question 12

A: Please find below the reaction

Q: 7. Propose a mechanism for the synthesis of 2-methyl, 2-butanol from 2-chloro-2- methylbutane using…

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Q: Br trace .CH.CH,CH; acid HCI, H2O Y ZI +

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Q: Mustard gas, Cl¬CH2CH2¬S¬CH2CH2¬Cl, was used as a poisonous chemical agentin World War I. Mustard…

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Q: Upon treatment with Tollen's reagent, you would expect one of these compounds to be unreactive. OH…

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Q: NH2 HO Atenolol Tenormin® Below is a two-step reaction sequence. What are the steps in the…

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Q: ) What is the name of the compound below? a) 3-oxopentanoic acid b) 1-acetopentanone c)…

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Q: Ме Me, Ме + Ме CI Ме

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Q: What reagent would you use to do this reaction? H2N OH O a) HgSO4, H30*. O b) KMNO4 O c) Cro3 O d)…

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Q: 90. What compound lucidin, rubiadin and munistin are belong? A) chrysacin derivatives B)…

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Q: Im sorry but i dont understand the following: "Hi and thanks for your question! Unfortunately, per…

A: Since the N is having a + charge on it. So it will lose try to take the electrons from the N-H bond.…

Q: compounds nag tul louwest pka value 13 Iklhicn O tue following the following Ccircde your angwer) ?…

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Q: 10 10.a)Draw the structure of cyclobutylmethanol. 10.b) Treat this molecule first with tosylchloride…

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Q: la. Show the reaction needed to prepare propyl phenyl ketone from CH,CH,CN and a Grignard reagent.…

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Q: Is fexofenadine chiral? If so, which of the possible stereoisomers are formed in this synthesis?

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Q: Select the single best answer. What reagents are needed to convert phenylacetylene into acetophenone…

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Q: 40. Which sacleophile would afford the greatest amount of the substitution product shown below? Br…

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Q: 1. What reagent will be used for this reaction? ??? ОН ОН 2. What is the needed carboxylic acid to…

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Q: Give two Friedel–Crafts acylation reactions that could be used to prepare 4-methoxybenzophenone. One…

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Q: 7. Enols react as a. Electrophiles.....alkenes b. Electrophiles....alkanes c. Nucleophiles...alkenes…

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Q: 20:24 : E) 03 12. Fill in the box with the major organic product of the first step of the reaction…

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Q: A student wanted to synthesize 4-(5-methylhex-3-yn-1-yl)phenol. The student's key step was to be the…

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Q: Alkyl Halides (X = CI, Br or I): Assume AICI, is present if needed 2 of 2 C D G H. un acid catalyst…

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Q: CH₂ CH₂ H KMnO4 H₂C 61. What type of reaction is catalyzed based on the chemical equation? A.…

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Q: OH - NH, Br2/KOH →product; 1. (a-hydroxy amide) Product of this Hoffmann bromamide reaction is : OH…

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Q: (c) Reaction of acetanilide with bromine Br: CH3 (d) Hydrolysis of 4-bromo-2-chloroacetanilide with…

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Q: Which one is INCORRECT? a.Br2 : electrophilic aromatic substitution b.Neutral KMnO4 : oxidation…

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Q: a) What two products are obtained when acetic anhydride reacts with N-isopropyl butanamine? Be sure…

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Q: Draw the products of the following reactions w given starting material 1. HCl 2. KMnO4 3. BH3…

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Q: In the Gabriel synthesis of primary amines, N-potassiophthalimide is used as a source of the…

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Q: Consider the following reaction schemes involving the reaction of an imine with an organolithium…

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Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.