Given are five KM values for the binding of substrates to a particular enzyme. Which has the strongest affinity when k-1 is greater than k2? 15 mM 1.5 x 10:12 M € 150 μ. 1.5 nM Recall, KM (k.1+k₂)/k1 k₂ E+S ES k₂ k₂ E+P

Given are five KM values for the binding of substrates to a particular enzyme. Which has the strongest affinity when k-1 is greater than k2? 15 mM 1.5 x 10:12 M € 150 μ. 1.5 nM Recall, KM (k.1+k₂)/k1 k₂ E+S ES k₂ k₂ E+P

Chemistry: The Molecular Science

5th Edition

ISBN:9781285199047

Author:John W. Moore, Conrad L. Stanitski

Publisher:John W. Moore, Conrad L. Stanitski

Chapter11: Chemical Kinetics: Rates Of Reactions

Section: Chapter Questions

Problem 83QRT

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Question

Given are five KM values for the binding of substrates to a particular enzyme. Which
has the strongest affinity when k-1 is greater than k2?
15 mM
1.5 x 10:12 M
€ 150 μ.
1.5 nM
Recall, KM (k.1+k₂)/k1
k₂
E+S
ES
k₂
k₂
E+P

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