For the nitration of toluene, to obtain m-bromotoluene yields similar to the ortho or para position, which condition should be folowed Use NBS (N-bromo-succinimie) instead of Br2. Use low temperature for kinetic control. OIt is impossible through this route since the methyl group is ortho, para directing. Use high temperature and pressure. of the nitronium ion?@GMU 2020

For the nitration of toluene, to obtain m-bromotoluene yields similar to the ortho or para position, which condition should be folowed Use NBS (N-bromo-succinimie) instead of Br2. Use low temperature for kinetic control. OIt is impossible through this route since the methyl group is ortho, para directing. Use high temperature and pressure. of the nitronium ion?@GMU 2020

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

Provide a plausible arrow pushing mechanism for the reaction below. Hint: NaOBr is in solution along with an excess of NAOH for the first step. 1. excess NaOH (aq), Br2 HO, NH + CO2 2. acidic workup NH2
B3. Write a detailed mechanism for the following Knorr Synthesis 1) (BUO-NO (0.5 equiv) , HCI A .CO2Et C14H21NO4 2) Zn, ACOH
Extra Credit: Reduction of Camphor Lab Below is a bicyclic compound that has two trifluoromethyl groups along with a ketone functional group. Using your broad knowledge of organic chemistry, you are to rationalize which of the potential final products would be in a major excess. In addition to a required mechanism, also include a detailed explanation as to why you have chosen the structure as the major product in the reaction. F. .F F 'F NABH4 CH;OH
Provide a plausible arrow pushing mechanism for the reaction below. Hint: NaOBr is in solution along with an excess of NaOH for the first step. 1. еxcess NaOн (ад), Brz OH + CO2 NH 2. acidic workup `NH2
a) Consider the substitution reaction shown below: n-Pr. Me Br Et organic product + H-Br H2O i) Predict whether the substitution mechanism is SN1 or SN2, rationalising your choice. ii) Draw a curly arrow mechanism that explains formation of the organic product. ii) With the aid of a diagram, rationalise the stereochemical outcome of the reaction. Provide a fully annotated Gibbs free energy diagram that describes the reaction. iv) With the aid of a diagram, discuss what stabilises the carbocation intermediate and what impact this has upon the rate of the reaction. v)
To preview image click here > Perform the retrosynthetic analysis for the indicated bond and choose the correct synthetic equivalents. :0: H+ A. B. H :0: OA OB O C OD Na 1: + + Na 1: C. H- + + Na :0: +Na D. H
Mechanism. Propose a mechanism for the following reaction. Label the rate-determining step and the major resonance contributor. Make sure to include (1) the formation of the electrophile and (2) all significant resonance contributors of the sigma complex intermediate. NO2 H2N H2N. HNO, (1 eq.) H2SO4 O °C CF3 CF3
.0. For 0.1 M equimolar reaction of CH3COOH + NH3 ----> CH3-CO-O™ + NH4+ How does the concentration of ]? [CH3COOH] compare to that of [CH3-CO-O (a) Equal (b) Greater than (c) Less than) (d) not possible determine a
Draw the structure(s) of the major organic product(s) of the following reaction. t at 1. lithium diisopropylamide / hexane t 2. 1 eq. CH2=CH-CH2CI ot • You do not have to consider stereochemistry. • Omit products derived from the acidic or basic reagent itself, e.g. HN(i-Pr), derived from N(i- ot t Pr)2". If no reaction occurs, draw the organic starting material. • If substantial starting material is present at the end of the reaction, include it in the products. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. • Separate structures with + signs from the drop-down menu. ot t ot
Section B (continued) В4. Answer all parts (i-iv). Explain the reactions and observations shown in the schemes below: Scheme 1 of + КОMe Me- C4H8 Br not observed product Scheme 2 H2SO4 nok + MEOH Me HO Your answer should address the following points: i) Explain why the SN2 reaction in Scheme 1, leading to formation of the ether does not take place. Predict the structure of the product C4H8 arising from the reaction in Scheme 1 above. ii) iii) iv) Provide the mechanism accounting for the formation of the product C4H8. Provide a rational for the formation of the ether in Scheme 2.
Provide a plausible arrow pushing mechanism for the reaction below. 1. ABULI ŅME2 2. MgCl HO,C, 3. CO2 4. acidic workup F NME2 NME2
ugateu. B NOT a resonanc + CHEM 242 Act 2.2 Aromatics Compounds and EAS Reactions 6. Provide the mechanism for the following reaction. Make sure to include the formation of the electrophile as well as any relevant resonance structures. HNO3 H₂SO4