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Anatomy and Physiology of Special Sensory Organs
Sensory organs can be labeled as special sensory structures that permit sight, hearing, odor, and flavor. Sensory structures permitting proprioception, touch, thermal, and pain perception can be classified as more advanced sensory organs. The sensory neurons are trained to find out modifications in the external and internal conditions so that a person's body can react to that change. A stimulus is the first signal that is recognized by any sensory receptor of the body. Stimulus is an impulse generated when there is a change in the surroundings of a person. For example, a heated environment will alert the brain through the thermal sensory organs and generate a reflex accordingly.
Sensory Receptors
The human sensory system is one of the most complex and highly evolved structures, which processes a myriad of incoming messages. This well-coordinated system helps an organism or individual to respond to external stimuli, appropriately. The sensory receptors are an important part of the sensory system. These receptors are specialized epidermal cells that respond to external environmental stimuli. These receptors consist of structural and support cells that form the peripheral unit of the receptor and the neural dendrites which receive and detect the external stimuli.
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- A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. Should the parents be concerned about the heterozygous condition as well as the homozygous mutant condition?A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. What is the chance that this couple will have a child with two copies of the dominant mutant gene? What is the chance that the child will have normal height?Dihybrid Cross gray hair dominant In rabbits, is dominant to white hair. Also in rabbits, black red eyes. These letters the eyes are to represent genotypes of the rabbits: GG = gray hair Gg = gray hair gg = white hair BB = black eyes Bb = black eyes bb = red eyes 1. What the phenotypes (descriptions) of rabbits that have the are following genotypes? Ggbb ggBB ggbb GgBb
- 三|三 主 主 13 ||L 4 6. 8. Construct a Punnett square for a cross between a heterozygous black guinea pig and a homozygous white guinea pig. a. What genotypes would you expect in the offspring? 5.While sitting at home during Movement Control Order (MCO) because of pandemic covid19, observe two different traits of a couple in your family (eg. your mom & dad or your sister & her husband or your brother & his wife, etc). Draw a genetic cross that involves cross of the parents with the chosen 2 pairs of their contracting traits. Imagine that the cross obeys the Mendelian Laws, show the cross and gametes production for each generation (P, F1 and F2). By Using a Punnet square as symbolic representation of the results for the cross, determine the phenotypes, genotypes, phenotypic ratio and genotypic ratio of F2 generation in the family.Dihybrid Cross Practice In a breed of dog called a Doberman, black fur is dominant to brown fur and floppy ears are dominant to straight ears. These letters represent the genotypes and phenotypes of the dogs: EE = floppy ears Ee = floppy ears bb = brown fur ee = pointed ears BB = black fur %3D Bb = black fur 1. A female dog with the genotype BBee is crossed with a male dog with the genotype bbEe The square is set up below. Fill it out and determine the phenotypes and proportions in the offspring. Ве Ве Ве Ве bE How many out of 16 have: black fur and floppy ears? be black fur and pointed ears? brown fur and floppy ears? bE brown fur and pointed ears? be
- A recessive epistasis cross gives in the F2 a 9:3:4 phenotypic ratio. What is the expected phenotypic ratio when the F1 (BbEe) is crossed with the double recessive homozygote (bbee)? Keeping in mind ee masks the expression of B.Purple flowers are dominant to white flowers. Identify the phenotypefor the following genotype Ff, FF, ff and determine if the genotype is heterozygous or homozygous. * For each row, you should select two columns. Purple flowers White flowers Heterozygous Homozygous Ff FF ff Brown eyes are dominant to blue eyes. Identify the phenotype for the following genotype BB, Bb, bb and determine if the genotype is heterozygous or homozygous. * 口 ロ口FAlpQLSfiOhfAvlhxzCSiUll_6rt-nU5b0WI73UmWOxkOw8OCwk01ng/formResponse B 1 2 Bb x Bb b 4 The fur in both parents in this cross is * 1 B B Bb x Bb b 3 4 brown black O homozygous dominant homozygous recessive 3. 近
- Genetic Crosses that Involve 2 Traits In rabbits, black hair is dominant to brown hair. Also in rabbits, long straight ears are dominant to floppy ears. These letters represent the genotypes and phenotypes of the rabbits: BB = black hair EE = long ears Ee = long ears ee = floppy ears %3D %3D Bb = black hair bb = brown 1. A male rabbit with the genotype BBee is crossed with a female rabbit with the genotype bbEe The square Is set up below. Fill it out and determine the phenotypes and proportions in the offspring. How many out of 16 have black hair Ве Ве Ве Ве and long ears? bE How many out of 16 have black hair and floppy ears? be How many out of 16 have brown hair and long ears? bE How many out of 16 have brown hair be and floppy ears?5 & :56M ******* 24 DIHYBRID CROSSES DRV 0 Stv T alı A @ zladenA 9160p2-id2 bns obidalbaneoviene da II\ MOD YR 21 $59A ... Create a dihybrid cross and determine the expected phenotypic percentages of the offspring of two corn plants both of which are heterozygous for colour and texture (RrTt X RrTt). Don't forget to include clear let statements, and follow the all six steps taught on solving genetics problems. insig moni nellog: bna. zoom. Consider the genotypes of two lines of chickens: thepure-line mottled Honduran is i/i ; D/D ; M/M ; W/W, andthe pure-line leghorn is I/I ; d/d ; m/m ; w/w, whereI = white feathers, i = colored feathersD = duplex comb, d = simplex combM = bearded, m = beardlessW = white skin, w = yellow skinThese four genes assort independently. Starting withthese two pure lines, what is the fastest and mostconvenient way of generating a pure line that has coloredfeathers, has a simplex comb, is beardless, and has yellowskin? Make sure that you showa. the breeding pedigree.b. the genotype of each animal represented.c. how many eggs to hatch in each cross, and why thisnumber.d. why your scheme is the fastest and the mostconvenient