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For acetate with a pKa of roughly 4.2, what is a lowest pH where this molecule could serve as a good buffer?
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- What will be the pH of a buffer solution containing an acid with a pKa of 5.4 with an acid concentration equivalent to that of its conjugate base?For an acid with a pKa of 5.00, what is the pKb of its conjugate base?What is the pKb of the conjugate base of a weak acid that has a pKa equal to 5.29 at 25ºC?
- For an acid HA with a pKa of 5.2, what is the ratio of the concentration of the conjugate base to that of the acid at pH 7.2.You need to perform an enzymatic reaction at pH 6.0. Someone suggests a weak acid with pKa of 5.5 as the basis of the buffer. Will this substance and its conjugate will make a appropriate buffer for your experiment? Why / why not?”similar to the question what is the pKa of formic acid when the pH of buffer is 4.18?
- I need help understanding why the ratio of Acetate:Acetic acid = 3.5:1 and why the total amount would be 4.5. The question was calculate the ratio of the concentrations of acetate and acetic acid required in a buffer system of pH 5.30. The pka of acetic is 4.76. Where is the 1 coming from in the ratio 3.5:1 The second part of the question said what if the question aked for the molar concentration of acetate and acetic acid in this buffer given that the over all buffer was 0.5 M. Why is the total amount 4.5?5. The pKa of acetic acid (HA) is approximately 4.8. If a solution of acetic acid is brought to pH= 4.8, what can we say about the concentrations of HA and its conjugate base A? a) The solution is acidic so there is more HA than A. b) HA is a weak acid so it dissociates easily and [A'] is higher than [HA]. c) Their concentrations are the same. d) We can't say, it depends on the initial concentration of HA. e) We can't say, it depends on temperature.5.Which substance would be the best buffer at pH 7.6 if it had to be able to buffer against either acid or base? A. one with a pKa of 5.6 B. one with a pKa of 7.6 C. one with a pKa of 9.6 D. The pKa of a substance doesn't tell you whether it would be a good buffer at this pH. 6.For the following reaction, which of the following is true? A B AG = +15.9 A. The conversion of A to B is spontaneous B. The conversion of A to B is exergonic C. Both A and B D. Neither A nor B
- Which of the following acid/ conjugate base pairs would function best as a buffer at physiological pH? Lactic acid / Lactate ion; pka = 3.86 Carbonic acid / Bicarbonate ion; pka = 6.37 Bicarbonate ion / Carbonate ion; pKa = 10.25 Dihydrogen phosphate / Monohydrogen phosphate ion; pKa = 6.86 Acetic acid / Acetate ion; pka = 4.763. The pH of the given solution of lactic acid and lactate is 4.30. Calculate the pKa of lactic acid, when the concentration of lactic acid and lactate are 0.020 M and 0.073 M respectively.In order to prepare a properly concentrated growth solution at work, your colleague asks you to prepare a citric acid-sodium citrate buffer, which has a pKa of 6.40. If the buffer should have a citric acid concentration of 0.95 M and a pH of 5.85, what concentration of sodium citrate do you need?
