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- 9. If the concentration of a plasma carrier was diminished, what would this do to the half-life of a steroid? a. increase half-life b. decrease half-life c. no change d. it depends on the steroid 10. Put the steps involved in generation and release of peptide hormones in the correct order: 1)cleavage into active hormone 2) transport into blood capillary 3)mRNA translation and preprohormone entrance into the ER 4) release signal into ECF 5)vesicular transport into Golgi apparatus 6)signal sequence peptide cleavage into prohormone11. Name the hormone(s) produced in excessive amounts that directly result in the following conditions. 1. in the adult: large bones of the hands, feet, and face 2. nervousness, irregular pulse rate, sweating 3. demineralization of bones, spontaneous fracturesMs. Reham is 39 years old woman has received a diagnosis of Graves' disease. Her thyroid laboratory values today include low TSH level and high free T4 level. She is anxious and always feels warm when others say it is too cold. Which is best for initial treatment of her condition: a. Atenolol b. Lugol's solution. c. Methimazole d. All the options are true.
- 1. Growth hormone can be described as being under _____ control? a. antagnostic b. synergistic c. tonic 2. The anterior pituitary is primarily responsible for regulating which of the following? a. steroid hormones b. peptide hormones c. amine hormones d. all of the above e. none of the above 3. A patient has a source of secondary pathology of hypercortisolism. Which association would you expect to see in their lab results? a. high CRH, low ACTH, low cortisol b. low CRH, high ACTH, low cortisol c. low CRH, high ACTH, high cortisol d. low CRH, low ACTH, low cortisol2. Explain how the hypothalamus and certain endocrine glands work together to maintain the following conditions in the body. Specify the endocrine glands involve and the hormones it releases.1. a. Identify the role of the endocrine system. b. List 4 examples of the endocrine system in action c. shortl explain the three ways hormone secretion is controlled
- 1. What are hormones? Discuss briefly the importance of hormones in the body. 2. Explain the ways in which hormones work.1. Norepinephrine and epinephrine act in a permissive manner to thyroid hormone. This means... A. Norepinephrine and epinephrine bind to TH receptors B. Norepinephrine and epinephrine antagonize the action of TH C. Norepinephrine and epinephrine upregulate the number of TH receptors, strengthening the effects of TH 2. Which mechanism of action is NOT common to both cortisol and growth hormone? A. Muscle building B. Mobilizing fatty acids8. Disorders of the Endocrine System: Fill in the table describing disorders of the Endocrine System. Type 1 diabetes mellitus A. Hypersecretion of cortisol – resulting in "moon face" and high blood pressure. Type 2 diabetes mellitus B. Antibodies produced by the immune system stimulate the thyroid gland resulting in hyperthyroidism, often accompanied with protrusion of the eyes. C. Hypersecretion of hGH during childhood causes a notable increase in height. Diabetes insipidus Cushing's syndrome D. Severe hypothyroidism. E. Destruction of the beta cells of the pancreas early in life results in low levels of insulin production. As a result, glucose cannot enter cells. Acromegaly F. Hyposecretion of hGH resulting in slow growth pattern and an unusually small stature. Gigantism Addison's disease G. Hyposecretion of ADH or the kidneys not responding appropriately to ADH causes the body to excrete large volumes of urine, resulting in dehydration and thirst. Myxedema H. Target cells become…
- 3. Complete the following table comparing steroid hormones to protein hormones Steroid Hormone Initial Binding Site (i.e. what it initially attaches to and where) Mechanism of Action Example (i.e. name one) Protein HormoneWhich of the following is a long-term side effect of carmustine?A. Adrenal dysfunctionB. Hearing lossC. Pulmonary fibrosisD. Solit tumor development5. Match the term with the definition. A. Local hormone that acts on the same cell that secreted hormone. Circulating hormone B. Most endocrine hormones; pass from the secretory cells that make them into interstitial fluid and then into the blood. Paracrine hormone C. Local hormone that acts on neighboring cells. Autocrine hormone Tropic hormone D. hormone that acts on other endocrine glands. 6. Match the hormone with the function. A. Synthesized by the hypothalamus and stored/secreted by the posterior pituitary - enhances contractions of the uterus; stimulates milk ejection from mammary glands; has actions with brain that foster parental caretaking behavior toward offspring. Human growth hormone Thyroid stimulating hormone B. Secreted by anterior pituitary - stimulates development and maturation of ovarian follicles in females; stimulates sperm production in males. C. Synthesized by anterior pituitary - increases protein synthesis, causing growth of bones and skeletal muscles,…