Explain in depth the Regulation of Glycogen Metabolism by Insulin and Glucagon.
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Explain in depth the Regulation of Glycogen
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- Describe the function of the insulin molecule in the body.Explain what biochemical pathway/metabolic processes are affected in insulin resistance? How does this affect glycogen breakdown and gluconeogenesis.Describe the mechanism of action of insulin and glucagon, and how they differ in relation to the blood glucose level.
- Compare the regulation of glucagon and insulin secretion after a mealhigh in carbohydrates, after a meal low in carbohydrates but high inproteins, and during physical exercise.What is feedback mechanism of hormonic regulation. Take the example of insulin to explain this phenomenon./Discuss, in terms of AMPK activity and GLUT4, how physical inactivity might lead to insulin resistance.