Diastereomers are a type of a stereoisomer. Diastereomerism occurs when two or more stereoisomers of a compound ha different configurations at one or more (but not all) of the equivalent (related) stereocenters and are not mirror images o each other. OH OH НО Но ÕH ОН How many chiral centers are present in one of the structures above? 1 O 2 O0 Are the structures mirror images of each other (i.e., are ALL of the chiral centers exactly opposite)? no yes I can not tell. How are these two structures related to each other? Diastereomers Non-isomeric (different molecular formulas) O Constitutional (same MF but different connections) Enantiomers (non-superimposable mirror images)

Diastereomers are a type of a stereoisomer. Diastereomerism occurs when two or more stereoisomers of a compound ha different configurations at one or more (but not all) of the equivalent (related) stereocenters and are not mirror images o each other. OH OH НО Но ÕH ОН How many chiral centers are present in one of the structures above? 1 O 2 O0 Are the structures mirror images of each other (i.e., are ALL of the chiral centers exactly opposite)? no yes I can not tell. How are these two structures related to each other? Diastereomers Non-isomeric (different molecular formulas) O Constitutional (same MF but different connections) Enantiomers (non-superimposable mirror images)

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter12: Chirality

Section: Chapter Questions

Problem 6E

See similar textbooks

Similar questions

91/ Draw examples of the following: a ) Ameso, Enantiomers and diastereomers compounds with the formula CaH18. b) Acompound with tow chirality centers (S, R) and (R, R). らに

The quantitative differences in biological activity between the two enantiomers of a compound are sometimes quite large. For example, the D isomer of the drug isoproterenol, used to treat mild asthma, is 50 to 80times more effective as a bronchodilator than the L isomer. Identify the chiral center in isoproterenol. Why do the two enantiomers have such radically different bioactivity?
Define the relationship between the molecules ( enantiomers , diastereomers structural isomers ( constitutional isomers ) , or identical . Locate the chiral centers and assign the absolute configuration for each of them .
7 For the following compound with two chiral centers assign 'R' and 'S' configurations. Draw enantiomers and diastereomers for the following compound? How many enantiomers and diastereomers are possible. Assign (R) and (S) configurations for all the structures. What are diastereomers? COOH H CI € Br -H CH3
If the asymmetric carbons in a molecule have been designated (2R,3S,5R), what will the designations be in the molecule’s enantiomer? What will the designations be in one of its diastereomers?
Identify each molecule as Chiral or Achiral and write the number of Asymmetric carbons present in each chiral molecules. Give explanation.
CH3 CHCH CHBrCH2 C≡C CH(OH)CH2CH3 Need to draw this 3D structure w/ chiral centers and come up with the name w/ stereochemistry
A well known non steroidal anti inflammation drug NSAID exists in two sterochemical forms. Only one is biologically active. Below is the structure of the biological active form. Identify the chiral center and determine if it is the R- or S- stereoisomer.
Assign the absolute configuration of the two chiral centers as R or S. он он CO₂H Both centers are S The center on the left is R; the center on the right is S Both centers are R The center on the left is S; the center on the right is R
Determine whether three molecules—H2O, CH2BrCl, and CHBrClF—aresuperimposable on their mirror images; that is, are H2O, CH2BrCl, and CHBrClF chiral or achiral?
How many carbon chirality centers does the molecule possess?
Use models (or drawings) to determine which of the following compounds are stable chiral molecules at room temperature. For those that are chiral, draw three-dimensional ( perspective) diagrams of the enantiomeric forms. H OMe OMe Bu Bu (HO2C)HC=C=CH(CO2H) HO₂C NH₂ CO₂H NH₂ (HO2C)HC=C=C=CH(CO2H)