Depolarization of membrane to threshold potential [ [ Choose ] up to threshold potential at the initial segment Conduction of action potentials along the axon [ [ Choose ] Opening of voltage-gated na+ channels [ [ Choose ] > >

Depolarization of membrane to threshold potential [ [ Choose ] up to threshold potential at the initial segment Conduction of action potentials along the axon [ [ Choose ] Opening of voltage-gated na+ channels [ [ Choose ] > >

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter4: Principles Of Neural And Hormonal Communication

Section: Chapter Questions

Problem 1RE: Conformational changes in channel proteins brought about by voltage changes are responsible for...

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Question

match the listed events to note if they would, or would not, occur in a neuron under the effects of tetrodotoxin. the cell has a resting membrane potential of -65mV. You should match these events at the initial segment of a bipolar neuron,

**Answer choice for all ( would occur, would not occur)

Depolarization of membrane to threshold potential
[
[ Choose ]
up to threshold potential at the initial segment
Conduction of action potentials along the axon
[
[ Choose ]
Opening of voltage-gated na+ channels
[
[ Choose ]
Increased influx of sodium
[
[ Choose ]
Inactivation of voltage-gated channels
[ Choose ]
Flux of sodium inside the membrante towards the
[ Choose ]
next anterograde Node of Ranvier
Release of neurotransmitters in from the neuron's
[
[ Choose ]
axon terminal
Closing of voltage-gated na+ channels
[
[ Choose ]
Opening of voltage-gated potassium channels
[
[ Choose ]
Closing of voltage-gated potassium channels
[
[ Choose ]
>
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Conformational changes in channel proteins brought about by voltage changes are responsible for opening and closing Na+ and K+ gates during the generation of an action potential. (True or false?)
Describe the action potential in terms of the different functional states of the voltage- gated Na+ membrane channels (Note: there are three states)
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Draw a typical action potential (correctly label axis) and explain in words the roles of ion channels in generating the different phases of the action potential. (Extra credit: How would opening voltage gated calcium channels upon depolarization affect the shape of the action potential if they have a relatively slow inactivation rate?)
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What is the expected resting membrane potential (in mV) of a neuron that is typical in all ways except for possessing an intracellular potassium concentration of 94 mM and double the normal resting permeability to sodium?
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