D. Write the multistep syntheses for the following targetcompound. 1ỌCH3D. Draw stepwise mechanism for the given amide. You can usehydroxybenzotriazole (HOBt) or 1-Hydroxy-7-azabenzotriazole(HOAt) as catalyst. 1N=C=NNH₂yfor ososNH₂Diisopropylcarbodiimide (DIC)

Note : Since you have posted multiple questions, we are entitled to answer the first only. Please…

Answered: D. Write the multistep syntheses for…

Science

Chemistry

D. Write the multistep syntheses for the following target compound. 1 OCH₂ NH₂

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter21: Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions

Section21.SE: Something Extra

Problem 46AP

See similar textbooks

Related questions

Q: QUESTION 4 What description of the organic product of this SN1 reaction is most accurate? ch7 d3…

Q: .a)The 1H NMR, 13C NMR, and the IR spectra of compound 2 are shown below. The molecular formula is…

A: Ozonolysis is reaction in which alkene is converted into corresponding carbonyl compounds either…

Q: Calculate the pH and the equilibrium concentration of CO32- in a 4.57x10-2 M carbonic acid solution,…

Q: quesion 2

A: Previous answer is correct the only wrong thing is in the final answer ....units of heat flows into…

Q: A chemist places 3.55 g of sodium carbonate in a 250 mL volumetric flask, and fills it to the mark…

Q: .An angular momentum occurs from the particle spinning on its axis

A: When a particle moves or spins about an axis of its own, there exists an angular momentum. For…

Q: Determine the pH if 50.0 mL of 0.50 M HI solution is added to 0.016 L of a 0.20 M KOH solution Your…

A: Here we are required to find the pH of the solution.

Q: For a fixed volume of gas at a fixed temperature, what will happen if the amount (number of moles)…

A: Ideal gas equation is PV=nRT P= pressure of the gas V= volume of the gas n= number of moles R=…

Q: The difference between a covalent and an ionic bond is that the covalent always donates its…

A: There are two types of bond Ionic bond Covalent bond Ionic bond is formed when one atom looses…

Q: How would you prepare ethyl isopropyl ether? a.) Reaction of ethoxide anion with 2-chloropropane b.)…

A: the alkyl halide is reacted with the conjugate base of the alcohol known as alkoxides. This is…

Q: 1. 2. A CO₂CH3 + OEt H₂C-PPh3 Bu₂N OH CO₂Et CO₂CH3 a = Electrophilic addition b = E2 Elimination c =…

A: A carbonyl nucleophilic addition reaction is a chemical addition reaction in which a nucleophile…

Q: Determine the pH during the titration of 12.3 mL of 0.339 M hydrobromic acid by 0.127 M sodium…

A: We need to find the pH during the titration of the strong acid HBr and strong base NaOH. The…

Q: A sample of a newly discovered element, West Virginium, has been discovered. A 501 mg sample has…

A: Radioactive decay follows first-order kinetics. The half-life of the first-order reaction does not…

Q: How many moles of HCl are in 298 mL of 2.3 M HCl (density = 1.03 g/mL)?

A: The molarity is a concentration term. It is defined as the ratio of no of moles of solute with that…

Q: Use the spectra on page 4 of the activity and the structure below to assign the CNMR spectrum of…

A: Given that the DEPT and the original 13C NMR spectrum of the molecule…

Q: Write a balanced equation for each reaction and determine which substance is oxidized and which…

A: First we need to write the reaction. Oxidised substance is that which lose electrons and whose…

Q: description element in Period 2 and Group 8A. nmetal in Group 6A. lkali metal with a lower atomic…

Q: Determine the most likely structure of a compound, with the molecular formula C9H12, which gave a ¹H…

A: Given, the 1H NMR data: a doublet at 1.25 a septet at 2.90 a multiplet at 7.25 We have to find the…

Q: 2NOC1(g) 2NO(g) + Cl₂ (g) Kc = 0.51 A mixture of NOCI, NO, and Cl₂ with concentrations 1.3, 1.2, and…

Q: for the reaction: 2 NaHCO3 → Na₂CO₂ + H₂O + CO₂ Find the mass of Sodium Carbmate that reacted from…

A: Given : mass of sodium bicarbonate = 1.56 g

Q: (a) A piston at 1.5 atm contains a gas that occupies a volume of 3.5 L. What pressure would have to…

Q: 5. What is the number of allowed energy levels with energies less than 20 eV for an electron in a 1D…

A: The particle in a box model describes a particle free to move in a small space surrounded by…

Q: 00 Aut P atm 49.8 र 1.00 0.00150- A. 930 54.4 54.8 •В T Kelvin Q 90.2 154.6

A: The phase diagram is a correlation curve between pressure and temperature conditions in all states…

Q: A chemical engineer must report the average volume of a certain pollutant produced by the plants…

Q: Suppose there is a gaseous mixture of nitrogen and oxygen. If the total pressure of the mixture is…

A: According to Dalton's partial pressure, the total pressure of a mixture will be the sum of the…

Q: Fluorine (F2), the most electronegative element reacts with water in a different way compared to…

A: Hess's law states that the enthalpy change for the overall reaction is determined from the sum of…

Q: 13C NMR Spectrum: 200 180 160 dd 120 100 ppm 80 60 40 20

A: 13C-NMR is used to determine the number of sets on non equivalent carbons in the molecule.

Q: It takes 348. kJ/mol to break a carbon-carbon single bond. Calculate the maximum wavelength of light…

Q: This energy diagram shows the allowed energy levels of an electron in a certain atom or molecule: E…

A: Energy is given by formula E=hv Where, h= planks constant v= frequency But v=c/λ Where c= speed of…

Q: You've decided to make your own handwarmers using NaOH and acetic acid (HC₂H3O2). If the kJ reaction…

A: Given : ∆H = -53.3 kj/mol

Q: Consider The Following Reaction: CaCO3(S) + 2HCl(Aq) = CaCl2(Aq) + H2O(L) + CO2(G) Write down the…

Q: C. How would you synthesize the given target compound in multistep syntheses? 2 HO CO₂H CH3

A: Multiple steps are involved

Q: What is the order of reactivity of SN1 and SN2 of n-butyl chloride, n-butyl bromide, sec-butyl…

A: For Sn1 mechanism, we look for the stability of carbocation formed, if it is more stable, more will…

Q: Provide the name of the following hydrocarbon.

Q: 2. Predict the transition metal-containing products of the following reactions and label which type…

A: “Since you have posted a question with multiple sub-parts, we will solve the first three subparts…

Q: A student determined the density of copper to be 8.31 g/mL. Calculate their percent error using the…

Q: O Macmillan Learning Ammonia, NH3, may react with oxygen to form nitrogen gas and water. 4 NH, (aq)…

A: Answer: Given chemical reaction: 4NH3(g)+3O2(g)→2N2(g)+6H2O(l) This question is based on the…

Q: C. What is the phase change associated with letter A when the pressure is suddenly dropped? e. 54.4…

A: (c) Letter A is initially in solid state. When the pressure is suddenly dropped, it goes down in the…

Q: How many isomers are possible using the following molecular formula? C3H6C12 h

A: The molecular formula given is C3H6Cl2.

Q: What is the order of increasing acidity for the following compounds? (least acidic to most acidic)…

A: In the above given compounds 3 compounds are carboxylic acid and 1 is alcohol. We know that…

Q: 2. mont bortimoteb A student performed the experiment as described, using 5.00 mL of an aqueous…

A: a.) We need to use conversion factor between inch and mm to calculate pressure in mmHg. b.) Using…

Q: A glass contains 250.0 g of warm water at 78.0°C. A piece of gold at 2.30°C is placed in the water.…

A: Given :- Mass of water (mw) = 250.0 g Temperature of water (Tw) = 78.0°C Specific heat of water…

Q: Problem 17.31 You have to prepare a pH 3.65 buffer, and you have the following 0.10M solutions…

A: We have to prepare a pH 3.65 buffer, and we have the following 0.10M solutions available: HCOOH,…

Q: A spent 1.0 percent caustic soda solution (ρNaOH = 8.42 lb/gal) with a volumetric flow rate of 3.0…

A: The density is defined as the mass of any substance present per unit volume. Density = massvolume

Q: Draw the major and minor products of this E1 reaction. Ignore any inorganic byproducts. H3O+ heat OH

A: When alcohols are heated in presence of acid they undergo dehydration to form alkene

Q: 3. Professor Jackson had an unknown alkene. She subjected it to ozonolysis and obtained two…

A: IR spectroscopy is used to determine the functional groups present in the sample. Different…

Q: Write a short note about IR spectroscopy instrumentation (source)?

A: IR spectroscopy is a major tool in chemistry for analysis. The IR spectra provide details about…

Q: Determine the empirical formula for the following made-up compound: X8Y12Z20

Q: The van Deemter equation decribes how the column, stationary phase, and linear velocity influence…

A: We have van Deemmter equation as, H≈A + Bux + Cux We need to find the terms in this equation.

Q: Ethanol, C₂H5OH, is used to introduce oxygen into some blends of gasoline. It has a heat of…

Question

D. Write the multistep syntheses for the following target
compound. 1
ỌCH3
D. Draw stepwise mechanism for the given amide. You can use
hydroxybenzotriazole (HOBt) or 1-Hydroxy-7-azabenzotriazole
(HOAt) as catalyst. 1
N=C=N
NH₂
y
for osos
NH₂
Diisopropylcarbodiimide (DIC)

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Step by step

Solved in 2 steps with 1 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

Draw the struetre of the following three isomeic amides with chemical feruula CHNO. Amide #1: (E)-N,N-dimethyl-2-butenamide Amide #2: (7)-N-methyl-3-pentenamide Amide #3: (7)-3-hexenamide C'onsider Z sterenchemistry of alkenes. • Draw one structure per sketcher. Add additional sketchers asing the drop-down memu in the hottom right comer. Sepamte structares with - signs from the drop-down mena. O00. IF ChemDoodle ChemDoodie ChemDoodle just the first one is what I could really use help on Amide #1: (E)-N,N-dimethyl-2-butenamide
D. Write the multistep syntheses for the following target compound. 1 D. Draw stepwise mechanism for the given amide. You can use hydroxybenzotriazole (HOBt) or 1-Hydroxy-7-azabenzotriazole (HOAt) as catalyst. 1 NH₂ olan yan to otor Diisopropylcarbodiimide (DIC) EtO₂C- OCH3 E. Write stepwise mechanism for the given reaction. 1 NH₂ ook OH F. Write stepwise mechanism for the given reaction. Write the role of DMF in the reaction? 1 CI CO₂H CI HÅN CI
NOC XT Ph CH₂ Both primary and secondary amines add to a ß-unsaturated aldehydes and ketones to yield ß-amino aldehydes and ketones rather than the alternative imines. Under typical reaction conditions, both direct and conjugate modes of addition occur rapidly. But because the reactions are reversible, they generally proceed with thermodynamic control rather than kinetic control so the more stable conjugate addition product is often obtained to the complete exclusion of the less stable direct addition product. Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instructions H H CH3NH₂ CH3 H-A :A Ph NHCH3 вон CH3 :A H-A 8b
Ch 11 Home de Dates > Ch 11 Homework O Resources Draw the products formed when the given amides are treated with aqueous potassium hydroxide. Reaction A Select Draw Rings More Erase OH КОН N. about us careers privacy policy terms of use contact us help (? SAMSUNG logitech O PO Print Screen Serol Lock Pause Break F12 F11 F9 F10 F8 F6 F7 F5 Home Page Up Insert 14
what amides would you treat with LiAlH4 to meke th following compound? benzylmethylamine
1. Which of the following amines would make an imine if reacted with an aldehyde or ketone? A B e. Which of the following moleculo C NH₂ AN D
If the following compound is saponified with sodium hydroxide, the products are: O || CH3(CH2) 14CH2-C-O-CH₂CH3 an ester and an alcohol an alcohol and a salt an acid and a salt an acid and an alcohol The purpose of the acid catalyst in the hydrolysis of an amide is: to enhance the nucleophilicity of the water molecule to enhance the electrophilicity of the amide carbonyl carbon to enhance the electrophilicity of the water molecule to shift the equilibrium of the reaction Which of the following compounds has the highest boiling point? CH3CH3 CH3CH2OH CH3-0-CH3 CH3COOH
Show how you would convert propan-1-ol to the following compounds using tosylateintermediates. You may use whatever additional reagents are needed. b) propan-1-amine, CH3CH2CH2NH2
Draw the major product formed from Hofmann elimination of the following amine. CH3 [1] CH3I (excess) [2] Ag,0 [3]A NH2
b с NH2 O N-methylhexanamide O 2-amino-N,N-diethylbenzamide 2-amino-N-methylbenzamide O N-ethyl-2-hydroxybutanamide 4-aminobenzamide N-ethyl-2-methylbutanamide Submit cyclopentyl acetate ethyl 3-hydroxy-2-methylbutanoate ethyl 3-oxobutanoate cyclopent-3-enyl propanoate ethyl 3-hydroxybutanoate cyclopent-3-enyl acetate
2262 Sat Aor 6 1 Which one of the following compounds is the strongest acid? CNH2 -NH2 -CO2H OH CI- СОН CH CH C A B 2. Which one of the following amines will not produce an amide when mixed with an acid chloride? NH PHCH,NH2 PHNH2 Et,NH A C 3. What is the major product of the following sequence of reactions? CH3 1) NBS, hv (excess) C(OH)3 CHO CO2H CH2O 2) NaOH, H20 (excess) A В C 4. What is the major product of the following intramolecular aldol condensation reaction? E NaOH H20 (dehydration) A C 3. D. B
Propose a structure for an amine with molecular formula CGH7N by interpreting the given 'H and 13C NMR data below. 1H NMR O 2.35 ppm O7.10 ppm 8 8.46 ppm singlet (3) doublet (2) doublet (2) 13C NMR 2, 4 1,5 6.00- 5.00- 4.00- 3.00- 2.00- 1.00- 0.00- 200 120 100 8/ ppm 180 160 140 80 60 40 20