Consider the sequence of reactions below. In this sequence of reactions, an unsaturated ketone is treated with a Gilman reagent, followed by treatment with an aqueous base. The base allows a rapid equilibration to take place, producing the more stable stereoisomer of the product. 1. Et,CuLi 2. Equilibration with base For this process: show both stereoisomeric products, explain which is more stable, and explain why aqueous base allows equilibration between the stereoisomers.

Consider the sequence of reactions below. In this sequence of reactions, an unsaturated ketone is treated with a Gilman reagent, followed by treatment with an aqueous base. The base allows a rapid equilibration to take place, producing the more stable stereoisomer of the product. 1. Et,CuLi 2. Equilibration with base For this process: show both stereoisomeric products, explain which is more stable, and explain why aqueous base allows equilibration between the stereoisomers.

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter16: Aldehydes And Ketones

Section: Chapter Questions

Problem 16.42P: When cis-2-decalone is dissolved in ether containing a trace of HCl, an equilibrium is established...

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