Consider a hypothetical enzyme that is COMPLETELY deactivated when a Valine (Val) residue buried in the core of the enzyme is mutated to Glutamate (Glu). In one or two sentences max, explain the MOST LIKELY reason for this occurrence.

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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Consider a hypothetical enzyme that is COMPLETELY deactivated when a Valine (Val) residue buried in the core of the enzyme is mutated to Glutamate (Glu). In one or two sentences max, explain the MOST LIKELY reason for this occurrence.

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