A mutation in Hb that prevented formation of the tetramer would result in: a   A decrease in overall O2 binding affinity but increased O2 transport to muscle. b   Increased O2 binding in muscle but decreased binding in lung. c   A loss of positive cooperativity and reduced O2 transport efficiency. d   All of the above.

Biochemistry
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Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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A mutation in Hb that prevented formation of the tetramer would result in:

a  

A decrease in overall O2 binding affinity but increased O2 transport to muscle.

b  

Increased O2 binding in muscle but decreased binding in lung.

c  

A loss of positive cooperativity and reduced O2 transport efficiency.

d  

All of the above.

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