A glycylglycine buffer is made to a pH of 8.45 at 25 ∘C then warmed to 37 ∘C. The pH of the solution changes because of the pKa changes. Glycylglycine has a p?a=8.26 and a Δp?a/Δ?=−0.026 °C−1. Calculate the pH of the buffer at 37 ∘C.

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter4: Acids And Bases
Section: Chapter Questions
Problem 4.18P: If the G for a reaction is 4.5 kcal/mol at 298 K, what is the Keq for this reaction? What is the...
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A glycylglycine buffer is made to a pH of 8.45 at 25 ∘C then warmed to 37 ∘C. The pH of the solution changes because of the pKa changes. Glycylglycine has a p?a=8.26 and a Δp?a/Δ?=−0.026 °C−1. Calculate the pH of the buffer at 37 ∘C.

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