A boy with Klinefelter syndrome (47,XXY) is born to a motherwho is phenotypically normal and a father who has the X-linkedskin condition called anhidrotic ectodermal dysplasia. The mother’sskin is completely normal with no signs of the skin abnormality.In contrast, her son has patches of normal skin and patchesof abnormal skin. Question: Which parent contributed the abnormal gamete?

Q: Sex determination of child is done by whose chromosome?

A: Chromosomes are the thread like structures which are located in the nucleus. There are 23 pairs of…

Q: In this pedigree, affected individuals have a disease causing the inability to walk forward, called…

A: Genes are the hereditary unit of an organism. The genes have DNA (deoxyribonucleic acid) which code…

Q: The autosomal (not X-linked) gene for brachydactyly, short fingers, is dominant to normal finger…

A: Brachydactyly is an autosomal dominant trait. Normal = bb Affected = BB, Bb

Q: What is the probability that a carrier wom en will transmit an abnomal X-linked gene to her son?…

A: Pedigree analysis is the pattern of analyzing the inheritance of disease/disorder from one…

Q: An individual named Pat with Prader-Willi syndrome produced anoffspring named Lee with Angelman…

A: Prader-Willi syndrome and Angelman syndrome are two different disorders which are associated with…

Q: A husband and wife have normal vision, although both of theirfathers are red–green color-blind,…

A: Since you have posted a question with multiple sub-parts, we will solve the first three subparts for…

Q: For the following chromosome complements, what is the phenotypic sex of a person who has Q. XO with…

A: The male sex-determining gene in human is termed as the sex determining region Y (SRY) gene.…

Q: Hemophilia A is transmitted by an X-linked recessive gene.With an affected father, what is the…

A: Answer: Introduction: In X-linked recessive disorders, an affected father has a mutation in a gene…

Q: The ABO blood type locus has been mapped on chromosome 9. A father who has type AB blood and a…

A: A cross is made between a father and a mother the father have an 'AB' blood group and the mother…

Q: What is the percentage chance that individual V.2 , will have inherited the X-linked recessive…

A: X-linked recessive diseases are the diseases which  are passsed from the female carrier to males. So…

Q: A boy with Klinefelter syndrome (47,XXY) is born to a mother who is phenotypically normal and a…

A: Meiosis is a type of cell division that occurs during gamete formation. It involves the reduction of…

Q: In humans color vision is X-linked, the gene for color vision is located on the X chromosome but is…

A: Colour blindness is a X linked Recessive disorder in which presence  of gene n on X chromosome is…

Q: In humans, one of the genes determining color vision islocated on the X chromosome. The dominant…

A: Sex-linked disorders generally have genes associated with the X chromosome. It is studied under the…

Q: Why is the development of individuals with Klinefelter's and Turner's syndromes relatively normal,…

A: This syndrome occur due to presence of an additional copy of X chromosomes resulting into karyotype…

Q: Duchenne muscular dystrophy, which is inherited in an X-linked recessive pattern, nearly always…

A: Muscular dystrophy is a group of diseases that cause progressive weakness and loss of muscle mass.…

Q: boy with Klinefelter syndrome (47,XXY) is born to a mother who  is  phenotypically  normal  and  a…

A: Klinefelter syndrome is a rare disorder that is caused in males alone. It is due to the presence of…

Q: Assume that a trait is determined by an X-linked dominant gene. Ifthe mother exhibits the trait but…

A: X-linked dominant disorders can be described as abnormalities that occur due to mutations in the…

Q: A human female with Turner syndrome (45,X) also expresses the X-linked trait hemophilia, as did her…

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: . In Figure 2-17, how does the 3:1 ratio in the bottom-lefthand grid differ from the 3:1 ratios…

A: Sex-linked genes are basically different from autosomes thereby, their inheritance pattern also…

Q: On rare occasions, people are born with a condition known as uniparental disomy. It happens when an…

A: Human contains two number of chromosomes 15, one inherited from mother (maternal) and one from…

Q: Why do X-linked recessive conditions appear most commonlyin males?

A: The genes are hereditary units of an organism. The appearance of the characteristics are a resultant…

Q: A family has an X-linked dominant form of congenital generalizedhypertrichosis (excessive…

A: Genes are the functional unit of DNA. It contains information that is transferred from one…

Q: Why are males affected by X-linked disorders much more oftenthan females?

A: Genes are the basic structural and functional unit of heredity. They carry coded genetic information…

Q: Why doesn’t the father (II-1) have the disease breast cancer? What is the formal name for an…

A: 1) The pattern of inheritance of the pedigree is autosomal recessive. The father (I-1) is…

Q: . Researchers discovered recently that the sole functionof the SRY protein is to activate an…

A: There are various genetic disorders that develop due to anomalies in sex chromosomes. They normally…

Q: The mutant FMR-1 allele that causes fragile X syndrome is considered to be X-linked dominant…

A: Fragile X syndrome is a genetic disorder. It causes various developmental disorders that include…

Q: A woman who sought genetic counseling is found to be heterozygousfor a chromosomal rearrangement…

A: Chromosome distortions remember changes for chromosome number (gains and losses) and changes in…

Q: Huntington disease is a rare dominant condition in humans that results in a slow but inexorable…

A: Huntington disease is an inherited neural disorder that causes the death of brain cells. The…

Q: For the following chromosome complements, what is the phenotypic sex of a person who has Q. XX with…

A: The sex-determining region Y (SRY) is located on the short branch of the Y chromosome, which…

Q: If a father is unaffected by an X-linked condition and the mother is a carrier, what is the…

A: Genetics is the branch of biology that deals with the study of heredity and variations. Gregor…

Q: Explain why a person with Klinefelter Syndrome (XXY) still exhibits abnormal phenotypes despite the…

A: The human sex is determined at the time of fertilization in the fallopian tube of the female…

Q: . A woman with Turner syndrome is found to be colorblind (an X-linked recessive phenotype). Both her…

A: Turner syndrome is a chromosomal disorder that impairs women's development. Half of the sex…

Q: The recessive, X-linked z1mutation of the Drosophilagene zeste (z) can produce a yellow (zeste) eye…

A: Gene is the specific sequence of nucleotide in deoxyribonucleic acid (DNA) or ribonucleic acid (RNA)…

Q: Can a son be a carrier for an X-linked trait? Explain.

A: The genetic makeup of an offspring is determined by the genetic makeup of both parents; that is, the…

Q: Could a woman who expresses the x-linked color-blind trait have a son with normal vision?

A: BASIC INFORMATION  COLOR BLINDNESS  it is an X - linked recessive trait  in this the eye is not…

Q: You have spent two decades studying a muscular dystrophy disorder. All previous pedigree data…

A: X linked disease is a type of sex linked disease in which the mutation is present in X chromosome.…

Q: Duchenne muscular dystrophy is a recessive disorder caused by a rare,loss-of-function allele that is…

A: Duchenne muscular dystrophy (DMD) is a quickly progressive type of muscular dystrophy that happens…

Q: Why does a single X chromosome cause infertility and other abnormalities in Turner Syndrome…

A: Turner syndrome (TS) is a genetic disorder that mostly affects females. The clinical features of…

Q: I XHXh| XhY 2 XhY XhXhY A) If the nondisjunction event that gave rise to Il-2 occurred in the…

A: X-linked recessive disease X-linked recessive allele contains two words that are "X-linked" and…

Q: Researchers discovered recently that the sole functionof the SRY protein is to activate an autosomal…

A: Sex-determining region of Y (SRY) is responsible for maleness in males. Mutation in the SRY region…

Q: Duchenne muscular dystrophy (DMD) is caused bya recessive mutant allele of an X-linked gene…

A: Duchenne muscular dystrophy (DMD) is a progressive form of muscular dystrophy that results in muscle…

Q: Two mothers give birth to sons at the same time at a busy urbanhospital. The son of mother 1 has…

A: Introduction: Hemophilia is an X-linked condition that causes blood to clot improperly in those who…

Q: . In mice, the dominant allele Gs of the X-linked geneGreasy produces shiny fur, while the recessive…

A: In mice, the dominant allele Gs of the X-linked gene Greasy gives shiny fur. The recessive wild-type…

Q: Incontinentia pigmenti, a rare, X-linked dominant disorder inhumans, is characterized by swirls of…

A: Incontinentia pigmenti is a genetic disorder that damages the skin and is more frequent in females…

Q: In 1952, an article in the British Medical Journalreported interesting differences in the behavior…

A: In the given data, hemophilia is an X-linked recessive disorder. There are interesting differences…

Q: Give the typical sex-chromosome complement found in the cells of people with Turner syndrome, with…

A: Chromosome complement refers to the entire set of chromosomes in the nucleus of a cell in a…

Q: Clark Kent and Lois Lane Kent are about to have a (Super) baby. As Superman, Clark possesses amazing…

A: In humans, the 23rd pair of chromosome is called the allosome or the sex chromosome. In males, the…

Q: A boy with Klinefelter syndrome (47,XXY) is born to a motherwho is phenotypically normal and a…

A: XX is female and XY is male. Klinefelter syndrome is a condition when the male has one more extra X…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.