A 30 year old woman with a 2-year history of systematic lupus erythematous comes to the physician for a follow-upexamination. Her condition has been well controlled for 6 months with corticosteriods. She has felt well and has not had fatigue. Menses occur at regular 28 day intervals with normal flow. Her pulse is 76/min and blood presssure is 130/80 mm Hg. Physical examination shows pale mucus membranes. Laboratory studies show Haemoglobin 10.6 g/Dl( 14 g/Dl 1 year ago) Leukocyte Count 5000/mm3 Recticulocye count 3 % Platelet count 250,000/mm3 Serum heptaglobin 30mg/Dl (N=40-200) Urine urobilinogen 3 + A peripherla blood smear shows recticulocytosis and a few spherocytes. A direct antglobulin( coobs) test result is positive. Which of the following types of hypersensitivity reaction is the most likely cause of the patients anemia? (A) Type 1 ( immediate) (B) Type 2( Complement-mediated cytotoxic) (C) Type 3( Immune omplex mediated)\ (D) Type 4 ( Delayed)
16. A 30 year old woman with a 2-year history of systematic lupus erythematous comes to the physician for a follow-upexamination. Her condition has been well controlled for 6 months with corticosteriods. She has felt well and has not had fatigue. Menses occur at regular 28 day intervals with normal flow. Her pulse is 76/min and blood presssure is 130/80 mm Hg. Physical examination shows pale mucus membranes. Laboratory studies show
Haemoglobin 10.6 g/Dl( 14 g/Dl 1 year ago)
Leukocyte Count 5000/mm3
Recticulocye count 3 %
Platelet count 250,000/mm3
Serum heptaglobin 30mg/Dl (N=40-200)
Urine urobilinogen 3 +
A peripherla blood smear shows recticulocytosis and a few spherocytes. A direct antglobulin( coobs) test result is positive. Which of the following types of hypersensitivity reaction is the most likely cause of the patients anemia?
(A) Type 1 ( immediate)
(B) Type 2( Complement-mediated cytotoxic)
(C) Type 3( Immune omplex mediated)\
(D) Type 4 ( Delayed)
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