8. If nembutal is used to anesthetize patients at a dose of 0.09mg/g body weight and the of the solution is 60mg/ml. How many mL are needed to anesthetize a concentration 4 pound patient?
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- SOLVE THE FOLLOWING PROBLEMS OF DOSE CALCULATION, SHOW THE CALCULATIONS FOR EACH OF THEY: 1. An arthritic patient is taking 2 1/2mg of Rymadil three times a day. If each tablet contains 5mg, how many tablets will the patient take in 7 days? 2. The doctor orders Librium 50mg IM, it is available in a 100mg/ml concentration How many ml should be injected? 3. A Doctor prescribes procaine penicillin G for a 25lb patient and his dose is 40,000 units/kg. The concentration of the drug is 300,000 U/mL. How many mL should be managed? 4. A patient cuts his leg with barbed wire and develops an infection. The doctor indicates 500mg of amoxicillin BID, for 10 days. The capsules are available in 250mg. How many capsules should be dispensed? 5. A patient has worms. The prescribed treatment is orally at a rate of 1cc/10lbs. If he @ patient weighs 7 lbs, how many cc should be given? ISOLVE THE FOLLOWING PROBLEMS OF DOSE CALCULATION, SHOW THE CALCULATIONS FOR EACH OF THEY: 1. Atropine is given in doses of .5mg/kg. How much will a patient who weighs 3.5 lbs receive? An arthritic patient is taking 2 1/2mg of Rymadil three times a day. If each tablet contains 5mg, how many tablets will the patient take in 7 days? 2.Daisy (7 years old; 30 kg) is admitted to hospital for meningitis and requires a short intravenous infusions of cefotaxime. A dose of 50 mg/kg is recommended every 6 hours for the first 4 days. Only 2 g cefotaxime vials are available. The powder in the vials is dissolved with 4.0 mL of saline. Calculate the volume (in mL to 1 d.p.)of this solution which should be transfered to the 40mL syringe driver for a single infusion.
- Calculate how much you need for the following dosages 36 You have haloperidol injection 5 mg in 1 mL; amount required = 6 mg. 37 You have diazepam suspension 2 mg in 5 mL; amount required = 5 mg. 38 You have codeine phosphate syrup 25 mg in 5 mL; amount required = 30 mg. 39 You have co-trimoxazole injection 480 mg in 5 mL; amount required = 2,040 mg. What volume and how many ampoules do you need?Determine the maintenance dose (in mg) of tobramycin for a 65 year old male patient weighing 85 kg and measuring 5 ft 7, in. in height with a serum creatinine of 2.8 mg/dL. The loading dose desired is 1 mg/kg of ideal body weight and 1.8 mg/kg of ideal body weight for the maintenance dose. Report your answer as a whole number.When 100 mg of a drug is administered as an IV bolus dose, the plasma concentrations (ug/mL) observed over time (hr) can be described by the following equation: C = 3.6e-0.105t C= 3-6e AUC 36 6 -0.105t 5. Calculate AUC(0-0) 0-105 = 34.28 6. What is the volume of distribution? Dose 100 VD= Co 3-6 7. Calculate the clearance of this drug. CI = KXVD CI = 0•105 x 27-8 %3D %3D Cl=2.9 8. What IV dose would be required to produce an initial plasma concentration of 10 ug/mL?
- 100 mg dose of Drug X is administered via IV at 7 hours, blood drug concentration is 5 mcg/mL Half-life of the Drug X is 5 hours A. Find the blood concentration after 6 hours if the dose is 1g (should be between 50.39 and 61.6) B. Minimum effective concentration is 2 mcg/mL. IF the first dose was 100mg of Drug X, how many hours after the dose would reach to 2mcg/mL. (When should the 2nd dose be given). (should be between 12.06 and 14.74)SOLVE THE FOLLOWING PROBLEMS OF DOSE CALCULATION, SHOW THE CALCULATIONS FOR EACH OF THEY: 10. To anesthetize a patient, a 10 ml bottle of Ketamine is available at a concentration at 10% If the Ketamine dose in patients is 15 mg/Kg and the patient weighs 4 lbs. Calculate: a) Weight of the patient in Kg. b) mg of Ketamine needed to anesthetize the patient. c) Volume in ml of Ketamine.A drug has been developed for oral administration as a rapidly dissolving capsule. This drug is also available as an intravenous formulation. Pharmacokinetic studies with both formulations in a relevant patient population provided the following values for absorption rate constant, clearance, volume of distribution and bioavailability: ka = 1.0 h-1; Cl = 9 L/h; V = 90 L; and F = 0.8. Calculate the drug concentration (in the blood) 8 h after a 1000 mg dose is administered orally.
- SOLVE THE FOLLOWING PROBLEMS OF DOSE CALCULATION, SHOW THE CALCULATIONS FOR EACH OF THEY: 6. The doctor prescribes aminophylline three times a day for 14 days to a 15-pound patient. if the dose is 10mg/kg. How many mg does the patient consume per day? How many in 14 days? 7. A sick patient weighs 3.5kg, you should give him 20mg/lb of a QID drug. what is the dose total?A medication order for a patient weighing 70 Kg is 0.75 mg of ampicillin per Kg BW to be added to 900 mL of 5% dextrose injection. The ampicillin injection is to be obtained in 2.5 mg/mL ampule. What is the total volume in mL of the IV admixture? Choose the best answer.