2 8. Identify the inhibitor from the following list for the selective target of thehaving C73 in the sequence of 7651 TOLMPFG C773 LL D Y VREH781Explain for the reason of selectivity.enzymeHNHNBrBrHNBrMeO.MeO1What type of inhibitor of Imatinib is ? Identify the H-bonding site with the hingeregion and the other binding interaction(s) with the kinase.ImatinibMeMe

o Acrylamide groups act as Michael acceptors and thus react with nucleophiles like thiol (SH) groups…

8. Identify the inhibitor from the following list for the selective target of the enzyme having C in the sequence of 7651 TOLMPFG CTS LL DY VREH781 Explain for the reason of selectivity. HN HN Br Br HN Br N. N. MeO. N. N. N' N. H. N' MeO What type of inhibitor of Imatinib is ? Identify the H-bonding site with the hinge region and the other binding interaction(s) with the kinase. .N. N. N. "Me Imatinib Me

8. Identify the inhibitor from the following list for the selective target of the enzyme having C in the sequence of 7651 TOLMPFG CTS LL DY VREH781 Explain for the reason of selectivity. HN HN Br Br HN Br N. N. MeO. N. N. N' N. H. N' MeO What type of inhibitor of Imatinib is ? Identify the H-bonding site with the hinge region and the other binding interaction(s) with the kinase. .N. N. N. "Me Imatinib Me

Pushing Electrons

4th Edition

ISBN:9781133951889

Author:Weeks, Daniel P.

Publisher:Weeks, Daniel P.

Chapter5: Some Reactions From Biochemistry

Section: Chapter Questions

Problem 16EQ

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