7. Compound X is an antibacterial drug of the sulfonamide group, and was widely used in the mid-20th century as one of the earliest antimicrobial drugs. X is synthesized through the following sequence of reactions. Draw structures of A-C and X, and show mechanism for the reaction C to X. NO2 NO2 1) NaNO2, H*, H20 H202 NH3 B H2 NaSH > X ZrCl4 Pd 2) O=$=0 H2N `NH2 NH2

7. Compound X is an antibacterial drug of the sulfonamide group, and was widely used in the mid-20th century as one of the earliest antimicrobial drugs. X is synthesized through the following sequence of reactions. Draw structures of A-C and X, and show mechanism for the reaction C to X. NO2 NO2 1) NaNO2, H*, H20 H202 NH3 B H2 NaSH > X ZrCl4 Pd 2) O=$=0 H2N `NH2 NH2

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter22: Carbonyl Alpha-substitution Reactions

Section22.SE: Something Extra

Problem 26MP: Nonconjugated , -unsaturated ketones, such as 3-cyclohexenone, are in an acid-catalyzed equilibrium...

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