6. With the presence of fast-food chains, many people have the opportunity to«have a quick bites while their daily physical activity is decreased. Explain whysuch a diet leads to obcsity more quickly under hypodynamic conditions. Foranswer:a) draw the charts of metabolic pathways in adipocytes with their activationleading to increased weight;b) give the origin of substrates, enzymes, ways of using final products;c) draw an appropriate chart and describe the stages of sequential hormonalsignal transduction to adipocytes and explain the biological effects of thehormonc.

Carbohydrate catabolism is the process by which carbohydrates are broken down to provide energy in…

Answered: 6. With the presence of fast-food…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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6. In an experiment, students used liver tissuc samples to study the cthanol metabolism and the possibility of ethanol conversion into glucose. The ethanol introduction in the investigated medium didn't lead to glucose level increase. Why is it impossible to convert ethanol to glucose? For the answer: a) provide a scheme of gluconcogenesis, indicate the substrates of this process; b) write the reaction of ethanol oxidation in the liver; c) explain whether it is possible to use the metabolites of ethanol catabolism for the glucose synthesis.
2. A well-trained athlete is running 5 km. What is the difference in glucose metabolism in the liver and muscle by the end of the race? For the answer: a) write a diagram of glucose metabolism in the liver in this case; b) draw a metabolic pathway of glucose in muscles; c) name regulatory enzymes and describe the mechanism of their activation; c) explain the significance of the metabolic pathways that occur in the liver and muscle. 3. The ATP source for the olucose synthesis from Jactate can be the conversion
Listed are some hypothetical medical conditions, describe their effect on cellular respiration (specifically refer to the effect they will have on energy production). a) A person is unable to take glucose into their cells. b) A mutation occurs in the ATP synthase protein and it is inactive. c) The mitochondrial inner membrane is very permeable to H+.
Q) Glycolysis and Gluconeogenesis are regulated through differential regulation a) What does differential regulation mean? b) Provide an example of a differential regulator from glycolysis (vs gluconeogenesis) • State what enzyme it regulates in glycolysis and what kind of regulator it is • In less than 10 words state what physiological conditions it signals.
The enzyme Phosphofructokinase (PFK) is a key regulator of glycolysis. A) Does ATP bind the PFK allosteric siteor the active site? B) Does high amount of ATP in the cell activate or inhibit PFK? Why? C)What do you suppose happens to glucose if glycolysis is inhibited in the cell?
Describe how a) Mean Arterial Pressure, b) Maximal Oxygen Consumption, and c) Blood Flow are determined using its formula. In addition, you should explain what those factors are including cardiac output, stroke volume, heart rate, resistance, a-vO2 difference, etc. Describe how many ATPs can be generated by complete cycles of beta oxidation of free fatty acid with 20 carbons. You should indicate how many cycles of beta oxidation and Krebs cycle, and total number of products as well
DCCD (diocyclohexylcarbodiimide) inhibits oxidative phosphorylation when the substrate is mitochondrial NADH. DCCD is a drug that binds to ATP synthase and blocks proton transport through the ion channel. a) Explain what the consequences of DCCD on cellular energy production are. b) Suggest at least one other cellular effect of DCCD and explain this effect.
10) The glycerol phosphate shuttle functions in. A) Lipid catabolism C) Anaerobic glycolysis for the regeneration of NAD 8) Triglyceride synthesis D) Aerobic glycolysis to transport NAH equivalents resulting from glycolysis into mitochondria. 11) In muscles, the pyruvate is converted into lactate. Find the correct statement A) During lactate formation, NADH is reconverted into NAD B) During the product of lactate two AT are produced C) Lactate is the substrate from the downstream pathway D) Lactate acts as the substrate for the formation of amino acid 12) Which of the following regulates lipolysis in adipocytes A) Activation of fatty acid synthesis mediated by CAMP 8) Glycerol phosphorylation to prevent futile esterification of fatty acids C) Activation of triglyceride lipase as a result of hormone stimulated increases in cAMP levels D) Activation of cAMP production by Insulin 13) Glycolysis consists of three irreversible steps. Which of the following enzyme catalyzes the reaction are…
2. After getting 300 g of carbohydrates with her meal, a student went to bed. What metabolic pathways of fatty acids have been activated in the liver about an hour after having a meal? For the answer: a) describe the glucose metabolism in the liver in this condition; b) name the metabolic pathway of fatty acids which has been activated; c) draw the scheme of this pathway and explain the fate of the end products of the pathway in the liver; d) explain the regulation of the pathway.
● 1.) Draw out the pathway for the biosynthesis of the following glycerophospholipid starting with choline, glycerol and the component fatty acids as it occurs in the liver tissue. Show the structures of all reactants and products, as well as the names of the enzymes. You do not need to draw the structures of ATP, NAD+, CoA, etc., but do show them as reactants or products in the appropriate places. You do not need to show the mechanisms of the enzymes. What is the name of the phospholipid? Us jure O • DISM 91 3.C6H3 UG OSEMSA QE F CH₂ CABJAD C-H H H₂C-O-P-0- ACELOj Pro ! H₂ C 212 32 CH3 f H3C -N-CH3
Which of these is associated with production of ATP during glycolysis? (Select all that apply) a) Conversion of 1,3-BPG to 3PG b) Conversion of 1,3-BPG to 2,3-BPG c) Conversion of PEP to pyruvate d) Conversion of 2,3-BPG to 2PG e) Phosphorylation of glucose
In some tissues, glucose 6-phosphate is oxidized to pentose phosphates by the pentose phosphate pathway. a) Which tissues prefer this pathway and why? Explain in detail. b) Due to the fact that glucose 6-phosphate is also an intermediate for the glycolysis pathway, the regulation of glycolysis and pentose phosphate pathway is very important. NADPH plays a crucial role in partitioning of glucose 6-phosphate between glycolysis and the pentose phosphate pathway. Explain this role of NADPH in detail.

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