51. Monoamine oxidase inhibitor is used to treat certain types of major depressive and phobic anxiety disorders. The concentration of which of the following compounds is most likely to be increased as a result of this treatment? A. Tryptophan B. Tyrosine C. Epinephrine
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- a. Why is there an adverse interaction between monoamine oxidase inhibitors (MAOIs) often given for psychological disorders and an epi pen? b. Epi pens deliver a fast, large dose of epinephrine and are used by people suffering severe allergic reactions. As an AR agonist, epinephrine plays no role in allergic reactions, so why is it used?Please show the Mechanism of action of Sertraline by figures or images or diagrams? Please answer at your own easy words. I will rate you positive if you do so. Please don't use AI for answering this question.Exposure to the compound below is most effectively treated with? CI CI N do= O-P O CH3 CH3 Itranscript O A. atropine & trimethaphan O B. edrophonium and methacholine OC. atropine & pralidoxime O D. pilocarpine & pralidoxime O E. neostigmine OF. IV bolus of acetylcholine
- A patient has a tumour of the chromaffin cells in the adrenal medulla. Whilst awaiting surgery, he is treated with an antagonist which reduces the consequences of adrenal medulla overactivity by binding alpha adrenergic receptors irreversibly. Which one of the following drugs has he been treated with? Answers A - E A Clopidogrel B Lansoprazole C Aspirin Propranolol E PhenoxybenzamineTheoretically, which of the following could be used as a "screening biomarker" for Alzheimer's Disease (something you test for to see if the disease is present)? 1. Presence of hyperphosphorylated Tau. 2. Presence of 42aa B-amyloid peptide. 3. Amount of acetylcholine production. 4. Amount of glutamate production. O A. 1, 2 and 3 OB. 1 and 3 O C. 2 and 4 OD. 4 only OE. All of 1, 2, 3, and 4 are correct1. Jesse age 27 complaints of muscle spasm, sweating abdominal pain and diarrhea. You know that her temperature is 101, pulse is 120 and her BP is 186/92. In reviewing her medications you note but she is taking fluoxetine (Prozac) and Sertraline (Zoloft), which life threatening events may she be experiencing? a. Neuroleptic malignant syndrome b. Monamine oxidase crisis c. Serotonin syndrome d. Hyperpyrexia
- Define the following terms:a. metabolic syndromeb. hyperurisemiac. hypothalamusd. anorexigenice. orexigenicDescribe the changes that occur in each step of the mechanism. (The probable mechanism of action of chymotrypsin)Epilepsy is often treated with a combination of drugs such as carbamazepine and phenytoin (polytherapy). CYP3A4 is induced by phenytoin and carbamazepine. Carbamzeipine is cleared by CYP3A4, but phenytoin is not cleared by CYP3A4. What problems might you expect if (a) carbamazepine is removed or (b) phenytoin is removed from this two-drug regimen.
- 17. Define atropine. Discuss its mechanism of action, uses and side effectsAnswer the following: 1.) an indirect agonist that mimics the action of epinephrine and norepinephrine and either stimulate release or block the reuptake of the naturally occuring sympathomimetics 2.) Toxic concentration of alprazolam 3. The only approved indications for use of this drug is for the treatment of attention-deficit hyperactivity disorder (ADHD) 4. An elevated acetylsalicylic acid serum concentration will decrease serum pH and contributes to 5. the metabolism of acute salicylate poisoning follows what order of metabolism kinetic? 6. In TCA poisoning, why is hemodialysis not recommended as a way of treating patient? 7. after an IV administration of this drug an individual feels a pleasurable experience 8, First generation of the tricyclic antidepressant agents 9. An antidote of choice for iron overdose/poisoning 10. Pediatric toxic dose of salicylates 11. Lethal dose of Amphetamine for childrenMrs. Jackson, who suffers from seizures, has been stable on a phenytoin dose of 300 mg q.d. (qd or QD) for over a year. However, she has recently been experiencing periods of heartburn. When you ask her more about this, you find there are no red-flag symptoms. She has tried OTC antacids in the past, but did not like them. Instead, she has seen Nexium tablets advertised and wants to know if they would be suitable. Is this an appropriate choice of OTC treatment? Explain in detail and based on scientific reasoning.