5. A patient initially has a concentration of 50mg/L of morphine in her blood and 70mg/L in her cerebrospinal fluid. Suppose that the drug moves into the cerebrospinal fluid at a per-capita rate of .4 and that the amount that is moved back from the cerebrospinal fluid to the bloodstream is .2 . Suppose further that the metabolism of medicine in the bloodstream is .1 and the metabolism of the drug in the cerebrospinal fluid is .2 Blood cerebrospinal fluid ( brain ) Let x(t) represent the concentration in the blood and y(t) represent the concentration in the

Linear Algebra: A Modern Introduction
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Chapter6: Vector Spaces
Section6.7: Applications
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5. A patient initially has a concentration of 50mg/L of morphine in her blood and 70mg/L in her
cerebrospinal fluid. Suppose that the drug moves into the cerebrospinal fluid at a per-capita
rate of .4 and that the amount that is moved back from the cerebrospinal fluid to the
bloodstream is .2.
Suppose further that the metabolism of medicine in the bloodstream is .1 and the metabolism
of the drug in the cerebrospinal fluid is .2
Blood
cerebrospinal fluid ( brain )
Let x(t) represent the concentration in the blood and y(t) represent the concentration in the
brain area.
Finish this compartment diagram.
Explain why this is a mathematical model for this process.
dx
= -.5x + .2y
dt
dy
= .4x – 4y
dt
Solve for x(t) and y(t) given the initial conditions stated above. Simplify each expression as
much as possible and write them in the blanks below. On the next page you must show all of
your calculations.
X(t)=
Y(t)= .
Transcribed Image Text:5. A patient initially has a concentration of 50mg/L of morphine in her blood and 70mg/L in her cerebrospinal fluid. Suppose that the drug moves into the cerebrospinal fluid at a per-capita rate of .4 and that the amount that is moved back from the cerebrospinal fluid to the bloodstream is .2. Suppose further that the metabolism of medicine in the bloodstream is .1 and the metabolism of the drug in the cerebrospinal fluid is .2 Blood cerebrospinal fluid ( brain ) Let x(t) represent the concentration in the blood and y(t) represent the concentration in the brain area. Finish this compartment diagram. Explain why this is a mathematical model for this process. dx = -.5x + .2y dt dy = .4x – 4y dt Solve for x(t) and y(t) given the initial conditions stated above. Simplify each expression as much as possible and write them in the blanks below. On the next page you must show all of your calculations. X(t)= Y(t)= .
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