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- 14) Which of the following correctly ranks the steps in the secretory pathway? 1. Active PKA subunits phosphorylate targets in the cell, regulating function. 2. The catalytic subunits of PKA dissociate. 3. Gprotein a subunit exchanges bound GDP for GTP. 4. CAMP binds to the regulatory subunits of PKA, activating it. 5. Ga subunit dissociates from complex and activates adenylate cyclase. 6. Ligand (hormone) binds to receptor. 7. Activated adenylate cyclase produces CAMP from ATP.a. integral memebrane protein that crosses membrane multiple time b. lipid-linked membrane proteins c. peripheral memebrane protein d. integral memebrane protein that crosses membrane ince32. The uptake of a large amount of fluid into the tubule cells of the kidney is an example of: a. receptor-mediated exocytosis. b. receptor-mediated endocytosis. c. phagocytosis. d. pinocytosis. e. simple diffusion dau sed dle
- Which of the following statements about "leak channels" in the plasma mem- brane is correct? A. Proteins that form these channels bind to solutes to allow them to pass into the cell. B. They are passageways formed by proteins to allow water and ions to move passively through the membrane. C. They allow small ions and molecules to move between adjacent cells. D. They are formed by glycoprotein and proteoglycans to allow hormones to enter cells.32. The uptake of a large amount of fluid into the tubule cells of the kidney is an example of: a. receptor-mediated exocytosis. b. receptor-mediated endocytosis. c. phagocytosis. d. pinocytosis. e. simple diffusion riguWhich of the following statements about potency is correct? O A. Committed progenitors have more potency than totipotent stem cells. B. Multipotent stem cells have higher potency than pluripotent stem cells. C. Unipotent stem cells are different from normal somatic cells because they can self-renew. D. Adult tissues have many totipotent stem cells in their niche.
- 175. A 70-year-old man comes to the physician because of a 1-month history of heavy, pressing substernal chest pain that occurs when he walks up a flight of stairs. The symptoms are relieved by rest. The physician prescribes a drug to alleviate the symptoms. Within the cell, the drug acts by breaking down into a compound that binds to a protein to increase intracellular concentrations of cGMP, resulting in vasodilation. This binding most likely occurs in which of the following cell locations? A) Cytosol B) Golgi complex C) Mitochondria D) Nucleus E) Peroxisome F) Plasma membraneThe Na/K pump in epithelium cells that line the gut is an example of ______ transport and helps __ Select one: a. active, prevent the movement of Cl- outside the cell b. active, prevent the movement of Cl- inside the cell c. active, prevent the movement of Na+ outside the cell d. passive, prevent the movement of Cl- outside the cell e. passive, prevent the movement of Cl- inside the cell42. Integrins are associated with which of the follow functions? A. Physically linking cells to the extracellular matrix B. Informing cells whether or not tethering to certain extracellular matrix components has been achieved C. Facilitating motility by making and breaking contacts with the extracellular matrix D. All of the above
- Membrane carriers resemble enzymes except for the fact that carriersa. are not proteins.b. do not have binding sites.c. are not selective for particular ligands.d. change conformation when they bind a ligand.e. do not chemically change their ligands.42.The sodium/calcium exchanger (NCX) transports three sodium into the cell for every one calcium out of the cell. Given what you know about ion concentrations, which of the following is/are true? A. sodium is being transported against its concentration gradient B. sodium is being transported with its concentration gradient C. calcium is being transported against its concentration gradient D. calcium is being transported with its concentration gradient Using a cell line, you are experimenting on transporters in the laboratory. You apply to the cell a chemical that inhibits the Na+/K+ ATPase. What do you notice about other transportation mechanisms across the cell membrane? Choose all that are correct. A. symporters cease to work B. antiporters cease to work C. movement of ions thru channels is altered as concentration gradients diminish D. calcium ATPase ceases to work 44.The sodium/glucose transporter (SGLT)…Which of the following intracellular or plasma membrane proteins requiresCa21 for full activity?a. calmodulinb. janus kinase (JAK)c. cAMP-dependent protein kinased. guanylyl cyclase