3. The following question is designed to help illuminate syntheses with carboxylic acid derivatives. a. What reagents would you add to make a carboxylic acid from the following starting materials? (Note: some routes may require more than one step). R-X X Cl, Br, I OH OH b. Now that we have our carboxylic acid, fill in the following "Reagent Map" to all the carboxylic acid series interconversions. OH R1 R R `N-R₂ R1

3. The following question is designed to help illuminate syntheses with carboxylic acid derivatives. a. What reagents would you add to make a carboxylic acid from the following starting materials? (Note: some routes may require more than one step). R-X X Cl, Br, I OH OH b. Now that we have our carboxylic acid, fill in the following "Reagent Map" to all the carboxylic acid series interconversions. OH R1 R R `N-R₂ R1

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter9: Nucleophilic Substitution And Β-elimination

Section: Chapter Questions

Problem 9.54P

See similar textbooks

Similar questions

using proper lewis structures, draw the reaction between 4-secbutylphenol with aqueous sodium bicarbonate. structures must be represented as line drawings with all lone pairs and formal charges shown. Please answer fast I give you upvote.
1.Predict the main product of the following reactions 1) MgBr 1) NaBH,, EtOH. 2) Hо* 2) H30* HO H30* H2N´ PPH3 12 H2N-NH2 КОН CH;COOH OH OH 1) Ph,CuLi H,O* 2) H3O* 2) H,0* 1) -MgBr HCN 2) H30* KČN NH2 Ph,P=CHCH3 HO, 1) LDA 1) LİAIH. 2) 2) H3O* Br
1. Oxazolines (five membered ring with N and O shown below) are an important functional group in organic chemistry because they can be used to help facilitate catalytic, enantioselective reactions during the synthesis of important pharmaceutical molecules. One way to make oxazolines is through the ring expansion of N-acylaziridines. Me Ph Nal Acetone Ph An N-Acylaziridine An oxazoline a. This reaction utilizes nucleophilic substitution reactions to get from the aziridine to the oxazoline. Provide a complete arrow pushing mechanism for this transformation. You do not have to draw it while talking. You can have the mechanism already drawn out and simply talk through the steps. If you choose to use ChemDraw, be sure it is very clear where your arrows are pointing. You may also draw it by hand (paper or tablet) and screenshare an image of your work while explaining what happens. You must talk through each step of your mechanism and use proper terms such as nucleophile and electrophile. b.…
What is the best answer for the following reaction? OH Br H. A. 1) HO OH H,o 3) H,o 2) Mg, Diethylether B. 1) Mg, Diethylether 2) H30 3) HO OH H,o* с. 1) но OH H3O 2) Mg, Diethylether D. 1) Mg, Diethylether 2) HO он
Which reagent combination will produce the product shown? OH + En A) 1) MCPBA 2) H30* B) 1) Br2 2) H30* C) 1) KMNO4 2) H30* D) None of the above O A. A О В. В O C. C O D.D QUESTION 4 Which reagent combination will produce this product?
The blcyclic ketone shown below is first treaterd with a base, then ethyliodide is added to form the substituted ketone. Which base/conditions are sultable? 1) Base 2) O 1. Lithium diisopropylamide in THF at -78 "C. O 2. NaBH4 in methanol at room temperature. O 3. Sodium methoxide in methanol at room temperature. O 4. DBU in THF at 25 "C.
Draw the alkyl bromide for reaction 2. Select Draw Rings More Erase | 7 | | H Br Reagents Carboxylic Acid Product 1. Diethyl malonate, NaOC2H5, C2H5OH 2. NaOH, H2O 3. H3O*, heat ОН Draw the alkyl bromide for reaction 3.
3. Complete the reactions below: hium aluminium hydride CH,OH Tollen's Reagent Аз PCC (excess) A1 > A2 PHCH,NH, (excessi H Zn(Hg), HCI dilute chromic acid A8 A4 Brz, uv A5 A7 A6 HO. OH OH
What is the product of these reactions CTQ#2 (top one first)? OH OH OH CH3 & & ICH3 2 0 0 1,2 2,1 1, 1 2,2 -CH3 1. OSO 2. NaHSO3 1. mCPBA 2. H₂O*
3. For questions "A"- "C", complete the following reaction schemes (no mechanisms required). Show all reagents used in the order of application. th A) 6 B) ||| Ins HO HO
One of these reactions to prepare a carboxylic acid from an alkyl chloride fails. Which? Ya CI CI 1. NaCN 2. H₂O+ 1. Mg 2. CO2 3. H3O+ 1. Mg 2. CO₂ 3. H3O+ 1. NaCN 2. H3O+ CO₂H CO₂H CO₂H сон CO₂H
Answer the following questions for the reaction scheme below: OH e :CEN HIC N cyanide hydrogen cyanide phenol pka <= 10.0 pka = 3.46 a. The equilibrium favors the [Select] b. This reaction is best described as a(n) [Select] c. The strongest acid in the reaction is the [Select] [Select] d. The nucleophile in the forward reaction is e. The electrophile in the reverse reaction is [Select] phenolate %. ✓ reaction. 15 <