21 H3C HOH,C CHs CH3 CH3 OH 17 11 CH3 ÇH3 CH3 HO Pregnenolone Progesterone Cortisol 21 21 HOH,C HOH, CH3 HQ HQ OH 17 11 ÇH3 11 ÇH3 18 FIGURE 26.28 Pathways for the formation of progesterone, cortisol, and aldosterone. Corticosterone Aldosterone Progesterone H3C ÇH3 ÇHs CH3 OH OH 17 CH3 CH3 17«-Hydroxyprogesterone Androstenedione Testosterone CH3 CH3 HO FIGURE 26.29 Pathways for the formation of androgens and estrogens. HO Estrone Estradiol
21 H3C HOH,C CHs CH3 CH3 OH 17 11 CH3 ÇH3 CH3 HO Pregnenolone Progesterone Cortisol 21 21 HOH,C HOH, CH3 HQ HQ OH 17 11 ÇH3 11 ÇH3 18 FIGURE 26.28 Pathways for the formation of progesterone, cortisol, and aldosterone. Corticosterone Aldosterone Progesterone H3C ÇH3 ÇHs CH3 OH OH 17 CH3 CH3 17«-Hydroxyprogesterone Androstenedione Testosterone CH3 CH3 HO FIGURE 26.29 Pathways for the formation of androgens and estrogens. HO Estrone Estradiol
Anatomy & Physiology
1st Edition
ISBN:9781938168130
Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Chapter17: The Endocrine System
Section: Chapter Questions
Problem 23RQ: Cushings disease is a disorder caused by ________. abnormally low levels of cortisol abnormally high...
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Question
Congenital adrenal hyperplasia is a lifethreatening condition that results from a deficiency in the P450 enzyme steroid 21- hydroxylase. This enzyme catalyzes the first step in the conversion of progesterone into cortisol and aldosterone (Figures 26.28 and 26.29). A characteristic of congenital adrenal hyperplasia is an increase in sex hormone production. Explain why this is the case.
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