2. What is the major product of the following Friedel-Crafts alkylation? CH3 + CH;CHCH,CI AIC13 CH2CH2CH2CH3 I. CH,CH CH, CH2CHCH3 IV. П. CH3 CHCH,CH3 CH3 V. Ċ-CH3 CH3 III. A) I B) I| C) II D) IV E) V
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- 4. Reactivity. Propose a mechanism for each of the following transformations to explain the observed regioselectivity and stereochemistry. a. -COCI SiMe3 AICI3 Mé `Me 76% b. Me (Ph;P)4Pd (cat.) CO-Me EtzN, CH3CN, reflux Me MeO2C 80% с. Me Me SiMe3 n-BugNF DMF, HMPA 69% d. EtAICI (2 eq) toluene -SiMe3 85%A pentacoordinate carbon is a transition state in the mechanism. Seleccione una: O A. E2 O B. SN2 O C. E1 O D. SN1c. Snl reactions dominate under polar protic solvents. Increasing the polarity of the solvent will increase the rate of the reaction because the polar solvent will stabilize the dispersed charges on the transition state more than it will stabilize the neutral reactant. Label areas of ô* and & on the molecules of the transition state of the SN1 reaction below: Me Me Ме Me Me H20 Br -Br OH + НО \'H Et Et RDS Et H Et Et transition state not isolable carbocation intermediate not isolable
- - 1. Which of the following compounds would NOT produce the same major product as the others when treated with HCI? LIV b. C. II || IV III II d. e. III 2. Which of the following, when treated with HBr, would result in the formation of the same major product at both low and high temperatures? ||| v IV e. I V IV V*5. Which of the following organometallic reagents is most reactive? And why? A. CH3CH2CH2CH2Lİ B. CH3CH2CH2CH2MgBr C. (CH3CH2CH2CH2)2CULI D. (CH3CH2CH2CH2)2Zn E. (CH3CH2CH2CH2)2CdA -if the indicated property/behavior in item I is greater than in item II B-if the indicated property/behavior in item I is less than in item II. C- if the indicated property/behavior is equal in item I and item II. D- if the indicated data is insufficient to make a comparison.
- For Nos. 63-70 Choose: A -if the indicated property/behavior in item I is greater than in item II B-if the indicated property/behavior in item I is less than in item II. C- if the indicated property/behavior is equal in item I and item II. D- if the indicated data is insufficient to make a comparison.For Nos. 63-70 Choose: A -if the indicated property/behavior in item I is greater than in item II B-if the indicated property/behavior in item I is less than in item II. C- if the indicated property/behavior is equal in item I and item II. D- if the indicated data is insufficient to make a comparison. 63. Reactivity toward Nucleophilic Addition Reaction I. FCH₂CHO II. CH3CHOWhich conditions will cause the interconversion shown? how? H H2/ Lindlar catalyst oa. Li/ NH3lia) ob. H2 / PtO2 (1) Brg: (2) KOH / E:OH od. (1) Hg(OAc)2 / THF / H2O: (2) NaBH4 е.
- • what is the major product? 1. Og 2. DMS which of these mechanisms will succeed? CH,ONa THF 1. E1 2. E2 3. SNL 4. SN2Which set of reagents is appropriate for the following transformation? istryteps Br Br a. Br2/AIB13 b. 1. Br2/AIB13; 2.NANO2/HCl; 3. Fe/HCl c. 1. HNO3/H2SO4; 2. Sn/HCl; 3. Br2; 4. HNO2; 5. H3PO2 d. 1. HNO3/H2S04;B 2. Sn/HCl; 3. Br2/FeBr3; 4. HNO2; 5. НЗРО2What is the product of the illustrated mechanism? A A B B C C D D HAC H₂C A H- ,CH 3 O: H3C. CH3 ? H3C H3C. , CH 3 H3C. H3COH ధర్మం , వ O: HAC H3C P CH3 H B D CH3