2. Choose the correct statements about the eye development A. Hh, which is expressed by the developing photoreceptors in the posterior eye disc, induces cells in the morphogenetic furrow (MF) to express DPP, which is the ligand of DPP (BMP) signaling. B. Wg and Notch signaling inhibit while Hh and DPP promote the co-expression of RD genes including Ey. (Eyeless) and Eya (Eyes absent) in the preproneural (PPN) domain anterior to the MF. C. Eya, sine oculis (so), and Eyg (Eyegone) are the retinal determination (RD) network genes required for retinal determination and induction of atonal expression. D. EGFR signaling is required for the differentiation of all the photoreceptor neurons after R8 determination. In addition EGFR signaling is also required for maintaining cell survival in posterior eye discs. E. During Drosophila eye development, cell proliferation in the second mitotic wave is required to provide sufficient undifferentiated cells surrounding the differentiating photoreceptors for the stepwise recruitment of additional cell types into the developing ommatidia. F. Eyeless and Eyegone have similar structure and function as the mammalian Pax6 protein. Loss of function mutations of either ey or eyg cause loss of eye tissues and ectopic expression of either gene in wing discs will induce ectopic eye formation.
2. Choose the correct statements about the eye development A. Hh, which is expressed by the developing photoreceptors in the posterior eye disc, induces cells in the morphogenetic furrow (MF) to express DPP, which is the ligand of DPP (BMP) signaling. B. Wg and Notch signaling inhibit while Hh and DPP promote the co-expression of RD genes including Ey. (Eyeless) and Eya (Eyes absent) in the preproneural (PPN) domain anterior to the MF. C. Eya, sine oculis (so), and Eyg (Eyegone) are the retinal determination (RD) network genes required for retinal determination and induction of atonal expression. D. EGFR signaling is required for the differentiation of all the photoreceptor neurons after R8 determination. In addition EGFR signaling is also required for maintaining cell survival in posterior eye discs. E. During Drosophila eye development, cell proliferation in the second mitotic wave is required to provide sufficient undifferentiated cells surrounding the differentiating photoreceptors for the stepwise recruitment of additional cell types into the developing ommatidia. F. Eyeless and Eyegone have similar structure and function as the mammalian Pax6 protein. Loss of function mutations of either ey or eyg cause loss of eye tissues and ectopic expression of either gene in wing discs will induce ectopic eye formation.
Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter16: Gene Expression
Section: Chapter Questions
Problem 28CTQ: A scientific study demonstrated that rat mothering behavior impacts the stress response in their...
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Transcribed Image Text:2. Choose the correct statements about the eye development
A. Hh, which is expressed by the developing photoreceptors in the posterior eye disc, induces cells in the
morphogenetic furrow (MF) to express DPP, which is the ligand of DPP (BMP) signaling.
B. Wg and Notch signaling inhibit while Hh and DPP promote the co-expression of RD genes including Ey
(Eyeless) and Eya (Eyes absent) in the preproneural (PPN) domain anterior to the MF.
C. Eya, sine oculis (so), and Eyg (Eyegone) are the retinal determination (RD) network genes required for
retinal determination and induction of atonal expression.
D. EGFR signaling is required for the differentiation of all the photoreceptor neurons after R8
determination. In addition EGFR signaling is also required for maintaining cell survival in posterior eye
discs.
E. During Drosophila eye development, cell proliferation in the second mitotic wave is required to provide
sufficient undifferentiated cells surrounding the differentiating photoreceptors for the stepwise
recruitment of additional cell types into the developing ommatidia.
F. Eyeless and Eyegone have similar structure and function as the mammalian Pax6 protein. Loss of
function mutations of either ey or eyg cause loss of eye tissues and ectopic expression of either gene in
wing discs will induce ectopic eye formation.
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