2. A 65-year-old man has a carcinoma. Study of the neoplasm shows absence of class IMHC molecules and no tumor-specific antigens. An immunologic response from which ofthe following cells is most likely to lyse some tumor cells?OA) B lymphocytesB) y6-T lymphocytesOC) CD8+ T lymphocytesD) MacrophagesOE) Natural killer cells

Introduction:- Normal cells for express MHC 1 on them which helps in showing self tolerance to the…

Answered: 2. A 65-year-old man has a carcinoma.…

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter45: Defenses Against Disease

Section: Chapter Questions

Problem 8TYK

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5. Link the following 3 proteins with the most appropriate 3 cancer hallmarks: a) Matrix metalloproteinase b) TGF-beta c) Bcr-Abl.
16. Which cell type is derived from myeloid progenitors? A). Tec cell B). TH cell C). B cell D). Mast cell E), NK cell
1:Describe the various stages of T cells and the events that occur during each of these stages during T cell development. What stages of T cell development would be affected in mice with the following genetic mutations? Justify your answer. a) Mice that do not express MHC Class I molecule. b) Mice that do not express Rag1 c) Mice that do not express the pre-T-alpha chain 2:Transgenic mice that have constitutive expression of Rag1/2 are being used in an experiment to study pre-BCR signaling. Based on your knowledge of early B cell development, speculate on what might be the fate of BCR rearrangement and how will this affect further development of B cells in the bone marrow? please answer in full detail I want long well explained answers.
CD8 cells attack virally infected cells, usually killing them using what method? 1) Complement activation O2) 2) Apoptosis O 3) Phagocytosis O 4) Senescence
7. The major innate cell type to eliminate viral-infected cells are A). NK cells B). Neutrophils C). Macrophages D). Dendritic cells E). Tc cells. 8. Antibodies in the serum were secreted from A). TH cells B). Plasma cells C). Antigen presenting cells D). Naïve B cells E). Mature B cells 9. Which can initiate anti-viral responses? A). Tal cytokines released by epithelial cells. B). TH1 cytokines released by B cells. C). TH2 cytokines released by NK cells. D). TH17 cytokines released by basophils. E). All of the above.
4. The variable region can be found in Fab B). Fc C). CL D). TLR E). A, B and C 5. Which event primarily takes place in the thymus? A). Production of thyroid hormone B). Clonal expansion C). Antigen activation of lymphocytes D). Development of memory cells E). None of the above.
a) As a scientist trying to cure allergies, you would be happy to discover a drug that destroys all mast cells. How can this medicine help prevent allergies? What negative side effects can this drug have?b) Compare the defense mechanisms that occur in response to bacterial and viral pneumonia.
2. Plasma cells are which type of lymphocyte? Explain, No more than 3-6 sentences. A). T cells B). B cells
APC cells with antigen presented on MHC I can trigger which naïve cell type to activate, thus forming memory and effector cells? O 1) macrophages O 2) CD4 cells O 3) CD8 cells O 4) B cells
1. Please identify the WBC involved for each of the four types of leukemia. 2. Please assemble a collection of microscopy images for innate immunity and adaptive immunity. Underneath each image, please include • type of WBC • immune function Acute Myelogenous Leukemia (AML) Acute Lymphocytic Leukemia (ALL) Chronic Myelogenous Leukemia (CML) Chronic Lymphocytic Leukemia (CLL)
Removal of apoptotic cells are done by: Question 6 options: a) phagocytes or neighboring cells. b) circulatory system sweeping away the fragmented cells. c) fragmentation of the cell into small enough pieces that they are swept away by extracellular fluid. d) fusion of the apoptotic cell to neighboring cells to form multinucleate cells. e) migration of the apoptotic cells from the tissue to the lymphatic system to be flushed out.
1. The laboratory scientist who reviews the marrow reports that the bone marrow is overridden with plasma cells—so much so that clusters of plasma cells can be seen. What is the function of plasma cells? Explain with no more than 3-6 sentences. A). To present foreign antigens to immune cells B). To directly attack foreign cells when foreign antigens are recognized. C). To phagocytize cells with foreign antigens. D). To produce immunoglobulins specific to foreign antigens presented by T helper cells. 2. Immunoglobulins are made mainly of what substance? Explain. A). Carbohydrate B). Lipid C). Protein

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