17. Melittin is a 26-amino acid polypeptide found in bee venom. In its monomeric form, melittin is thought to insert into lipid-rich membrane structures. Explain how the amino acid sequence of melittin accounts for this property. Gly-le-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro 35 hr-Gly-Leu-Pro NH-GIn-Gln-Arg-Lys-Ang-Lys-le-Trp-Ser-le-Leu-Ala
Q: State the steps of ketone body formation, starting with two acetyl CoA. Please make sure to state…
A: Acetyl-CoA formed during oxidation of fatty acids in the liver, either enter the citric acid cycle…
Q: An enzyme catalyzes a reaction at a velocity of 20 μmol/min when the concentration of substrate…
A: To determine the reaction velocity (V) at a substrate concentration of 1 × 10^(-6) M using…
Q: Based on the list of intra- and extracellular concentrations shown below, ( ) is probably used as a…
A: Change in Gibbs free energy (∆G) of ion transport is given by the equation shown below. ∆G = ZF∆ψ +…
Q: If the chyme did not contain sodium, the absorption of which of the following would be impacted? O…
A: In animals, ingested food is stored in the stomach. Partial digestion of ingested food via gastric…
Q: How many net ATP are produced from the complete oxidation of one molecule of 1,3-bisphosphoglycerate…
A: 1,3 -bisphosphoglycerate is an intermediate formed in the process of glycolysis. It is a three…
Q: You are working with a 60 kDa protein that you want to visualize on a SDS-PAGE. What % separating…
A: For visualizing a 60 kDa protein in SDS-PAGE, a 12 % separating gel will be used.
Q: 5. Give the major product of the following reaction. OH H+, water, heat
A: The provided reaction is an instance of the dehydration process known as "acid-catalyzed dehydration…
Q: Amino Fatty acids acids Glucose Pyruvate Oxaloacetate Acetyl-CoA Glycolysis CO₂ NADH Acetyl-CoA…
A: Metabolism is a term that is used to describe all chemical reactions involved in maintaining the…
Q: Proteins undergo  a process, called folding to establish their final, functional configuration.…
A: As per the central dogma of molecular biology, DNA contains the information needed to synthesize…
Q: (a) H* transport from the outside of the IMM into the matrix drives this process. Assume the pH…
A: pH of inside the matrix=8.0 Concentration of H+ ion inside the matrix=1.0 A-10-8.0 pH outside the…
Q: Describe the unique fate of organic carbon and phosphorus during sequential anaerobic-aerobic…
A: Sequential anaerobic-aerobic cycling refers to a wastewater treatment process that involves…
Q: A PCR reaction was performed to amplify the XULA4 gene, which is bp 524-6,480 on a plasmid that is…
A: A plasmid is a circular DNA. Restriction enzymes cut DNA at specific sites called the restriction…
Q: Draw both possible disaccharides of D-psicose and D-mannose that are joined by an α(1→4) glycosidic…
A: A carbohydrate in which the anomeric hydroxyl group (hydroxyl group attached to the C1 carbon) is…
Q: Which three foods (from the table above) could each be eaten with rice as a complementary protein?
A: We are asked to come up with 3 complementary protein diets and the condition is that one of the food…
Q: Which of the following is the fourth step of glycolysis? Select one: a. Phosphoenolpyruvate is…
A: The metabolic process by which a glucose molecule is broken down into two molecules of pyruvate with…
Q: 6. Riboswitches are RNA sequences found in the 5' untranslated region of messenger RNA (mRNA) that…
A: Riboswitches are regulatory elements that control gene expression in response to the binding of…
Q: Peptides are a linear (non branched) polymer made from amino acid residues. A protein consists of…
A: Inorder to understand what pKa is, let us try to learn how did we get the term pKa. Let us consider…
Q: Figure legend: Acetaldehyde levels are much higher in red populations, compared to blue populations.…
A: Alcohol metabolism primarily takes place in liver with the help of two main enzymes, alcohol…
Q: What are the properties of protein?
A: Proteins are large, complex molecules composed of amino acids linked together by peptide bonds. They…
Q: List the attractive interactions involved in secondary, tertiary, and quaternary protein structure.
A: The amino acid sequence of the peptide/polypeptide determine the three dimensional structure that…
Q: 6. Describe the active site of the enzyme, which is the place where the reaction occurs. In your…
A: The active site is the region of an enzyme where substrate molecules bind and undergo a chemical…
Q: The chemical structure of Coenzyme A contains the following except— a phosphoanhydride moiety. a…
A: Coenzyme A is a cofactor that acts as an acyl group carrier. It plays a significant role in…
Q: Which of the following is true regarding the oxidation of 1 molecule of palmitate to 8 molecules of…
A: The correct answer is: None of the above. The beta-oxidation pathway is the process by which fatty…
Q: 1. A toxin that inhibits the establishment of the proton gradient across the inner mitochondrial…
A: Toxins are substances created by plants and animals that are poisonous (toxic) to humans. Toxins may…
Q: What type of enzyme is responsible for initiating the process of glycolysis?
A: Glycolysis is the metabolic pathway that breaks down glucose into pyruvate, releasing energy in the…
Q: What is the net gain in ATP for ß-oxidation of palmitic acid (a sixteen-carbon fatty acid)?
A: For the complete oxidation of palmitic acid, it is first activated to its acyl-CoA form. This…
Q: A researcher is preparing a reaction mixture to test the activity of a protein. They combine the…
A: pH is the negative log of H+ concentration. The H+ concentration should be in molar (M). 1 μM = 10-6…
Q: C₂ 200 Ketone R-C=O Aldehydes H-C=O Ester RO-C=O Carboxylic Acid HO-C=O Choose the Carbons HH I…
A: The graph is that of 13C NMR. The X-axis gives the chemical shift value in ppm. Every functional…
Q: Suppose that you accidentally added twice as much enzyme to the reactions as intended. How would…
A: Enzymes are biological catalysts composed of proteins. These catalysts speed up chemical reactions…
Q: What’s the explaining difference between catabolism and anabolism? I need help
A: Metabolism refers to the process of interconversion of biomolecules and carrying out chemical…
Q: The potential below is a hemogoblin, It has four subunits - each shown in a different color. Each…
A: Hemoglobin is a protein found in red blood cells, allows oxygen to be transported within blood from…
Q: Discuss the principles behind the use of the following techniques in the diagnosis of viral…
A: Restriction Fragment Length Polymorphism (RFLP) is a laboratory technique used to identify genetic…
Q: Lipids Concept Map Add these terms to your concept map should include these concepts and details:…
A: Lipids are a diverse group of biomolecules with varied chemical structures and functions.…
Q: What protecting groups in solid-phase peptide synthesis NOT do? a)Activate the carboxlic acid to…
A: Protecting groups are transient changes of functional groups on the amino acids utilized to…
Q: Determine whether a salt bridge interaction can occur between the side-chains of each of the amino…
A: Protein folding occurs at four different levels: primary, secondary, tertiary and quaternary. At…
Q: Compare and contrast the aerobic respiration and fermentation in terms of pathways found in each,…
A: All organisms must respire to generate energy from food. There are two types of respiration: aerobic…
Q: Analyze the reaction below and identify the major class of enzyme that catalyzes the the given…
A: Enzymes are catalysts that enhance the rate of biochemical reactions. The enzymes perform their…
Q: Which photosystem (I, II, both or neither) is disrupted by each of the inhibitors? Explain how you…
A: Photosystem I (PS I) is mainly composed of the P700 reaction center, ferredoxin, associated NADP+…
Q: Evaluate the properties and biological roles of Carbohydrates
A: Carbohydrates serve as a predominant and vital energy source for organisms. They are broken down…
Q: The reaction catalyzed by the enzyme Malate Dehydrogenase is an example of oxidative decarboxylation…
A: False. The statement is false. The reaction catalyzed by the enzyme Malate Dehydrogenase is not an…
Q: 1. Using a diagram or analogy, explain how energy is generated and used between plants and animals.…
A: The plant and the animal cells can be viewed as tiny energy factories that can facilitate the energy…
Q: Consider the 20 standard amino acids and their structures. Choose a set of 6 amino acids that you…
A: Amino acids are biomolecules that have an amino group and a carboxyl group linked to the same carbon…
Q: 10. This diagram is of a mitochondrion. Which label shows the site of the electron transport chain?…
A: ETC consist of four protein complexes called Complex I, II, III and IV that transport electron…
Q: The acute phase proteins. C-reactive protein.
A: When there is an inflammation, infection, and tissue damage in our body, a class of proteins called…
Q: Determine if the following statement is true or false. Explain your answer. “Two molecules of…
A: Insulin is a peptide hormone, a signalling molecule. It is secreted by the pancreatic cells in…
Q: Which of the following is true of this compound? COO™ OOC a. It is found on the surface of both…
A: Sometimes enzymes or protein require a non protein component for their function. This non protein…
Q: antacids may neutralize too much stomach acid, which causes an imbalance in the bicarbonate…
A:
Q: State the steps of the beta-oxidation pathway. Please make sure to state all the enzymes and…
A: Beta oxidation (also β-oxidation) is the process by which fatty acids are broken down. Both…
Q: 15.14) The metabolic strategy of oxidative phosphorylation is to convert the chemical potential…
A: Oxidative phosphorylation is a metabolic process that takes place in the mitochondria, specifically…
Q: Can you give me more expalination of Oxidation Deamination formation of -ketoglutaric acid and NH4+…
A: Oxidative deamination is a biochemical reaction that involves the removal of an amino group from an…
Trending now
This is a popular solution!
Step by step
Solved in 3 steps
- Porcine dynorphin is a neuropeptide having 17 amino acid residues. Its structure is shown below. Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln 8. How does trypsin catalyze the hydrolysis of peptides? You can answer this question by identifying the amino acids involved and whether the hydrolysis is at their amino side or the carboxyl side or if particular amino acids end up at the N-teminal end or at the C-terminal end. 9. List down the different fragments that would result if dynorphin were cleaved by trypsin. 10. How does chymotrypsin catalyze the hydrolysis of peptides? You can answer this question by identifying the amino acids involved and whether the hydrolysis is at their amino side or the carboxyl side or if particular amino acids end up at the N-teminal end or at the C- terminal end. 11. List down the different fragments that would result if dynorphin were cleaved by chymotrypsin. 12. Cyanogen bromide is a chemical reagent which also cleaves peptide bonds.…Draw the structure of the peptide: Val-His-Leu-Thr-Pro-Val-Glu-Lys-Ser-Ala-Val-Thr What is the significance of the peptide described?Porcine dynorphin is a neuropeptide having 17 amino acid residues. Its structure is shown below. Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln How does trypsin catalyze the hydrolysis of peptides? You can answer this question by identifying the amino acids involved and whether the hydrolysis is at their amino side or the carboxyl side or if particular amino acids end up at the N-teminal end or at the C-terminal end. List down the different fragments that would result if dynorphin were cleaved by trypsin. . How does chymotrypsin catalyze the hydrolysis of peptides? You can answer this question by identifying the amino acids involved and whether the hydrolysis is at their amino side or the carboxyl side or if particular amino acids end up at the N-teminal end or at the C- terminal end. List down the different fragments that would result if dynorphin were cleaved by chymotrypsin. . Cyanogen bromide is a chemical reagent which also cleaves peptide bonds. What is/are…
- PLEASE DRAW the structure of the peptide: Val-His-Leu-Thr-Pro-Val-Glu-Lys-Ser-Ala-Val-Thr and describe what its significance is.After the polypeptide shown below was treated with maleic anhydride, it was hydrolyzed by trypsin. (After a polypeptide is treated with maleic anhydride, trypsin will cleave the polypeptide only on the C-side of arginine.) Gly-Ala-Asp-Ala-Leu-Pro-Gly-Ile-Leu-Val-Arg-Asp-Val-Gly-Lys-Val-Glu-Val-Phe-Glu-Ala-Gly-Arg-Ala-Glu-Phe-Lys-Glu-Pro-Arg-Leu-Val-Met-Lys-Val-Glu-Gly-Arg-Pro-Val-Gly-Ala-Gly-Leu-Trp In what order will the fragments be eluted from an anion-exchange column using a buffer of pH = 5?Draw Glu-His-Trp-Ser-Gly-Leu-Arg-Pro-Gly peptide. What is the net charge of this peptide at pH 3, 8 and 11? What can you say about pI value of this peptide?
- Treatment of a polypeptide by 2-mercaptoethanol yields two polypeptides that have the following amino acid sequences: Ala-Phe-Cys-Met-Tyr-Cys-Leu-Trp-Cys-Asn Val-Cys-Trp-Val-Ile-Phe-Gly-Cys-Lys Chymotrypsin-catalyzed hydrolysis of the intact polypeptide yields polypeptide fragments with the following amino acid compositions: (Ala, Phe) (Asn, Cys2, Met,Tyr) (Cys, Gly, Lys) (Cys2, Leu,Trp2,Val) (Ile, Phe,Val) Indicate the positions of the disulfide bonds in the original polypeptide. I don't understand how the order of amino acids in Step 2 was arranged. Please explain. Thank you.Treatment of a polypeptide by 2-mercaptoethanol yields two polypeptides that have the following amino acid sequences: Ala-Phe-Cys-Met-Tyr-Cys-Leu-Trp-Cys-Asn Val-Cys-Trp-Val-Ile-Phe-Gly-Cys-Lys Chymotrypsin-catalyzed hydrolysis of the intact polypeptide yields polypeptide fragments with the following amino acid compositions: (Ala, Phe) (Asn, Cys2, Met,Tyr) (Cys, Gly, Lys) (Cys2, Leu,Trp2,Val) (Ile, Phe,Val) Indicate the positions of the disulfide bonds in the original polypeptide.The melanocyte-stimulating peptide hormone a-melanotropin has the following sequence:Ser–Tyr–Ser–Met–Glu–His–Phe–Arg–Trp–Gly–Lys–Pro–Val(a) Write the sequence using the one-letter abbreviations.(b) Calculate the molecular weight of a-melanotropin, using data inTable
- Draw the structure of this peptide: N-Met-His-Tyr-Leu-Asp-Ser-Arg-Leu-CDraw a tripeptide gly-phe-alaAmino acids project from each polypeptide backbone in a β-sheet in an alternating fashion (oneabove the plane and the next below the plane – see Fig 3.8B). Consider the following proteinsequence: Leu-Lys-Val-Asp-Ile-Ser-Leu-Arg-Leu-Lys-Ile-Arg-Phe-Glu.a. Is there a pattern to these amino acids? If so, what is it? b. What does this sequence of amino acids mean for the hydrophobicity/hydrophilicity of theresulting β-sheet? c. Can you make a prediction about how the β-sheet will be arranged in higher levels of protein structure? If so, what prediction would you make?