14. Type 1 fucosidosis is a rare human disease. Patients cannot hydrolyze the disaccharide fucose, and as a result have severe neurological decline and die by age 6. The disease is due to a defect in the gene that encodes the lysosomal enzyme that breaks down fucose (α-1-fucosidase), and is inherited in an autosomal recessive manner. Jane and John have a child who has Type 1 fucosidosis. What is the probability that their next child will also have the disease? A. 4/4 or 100% B. No chance C. 3/4 D. 1/4

Biology (MindTap Course List)
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Chapter16: Human Genetics And The Human Genome
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14. Type 1 fucosidosis is a rare human disease. Patients cannot hydrolyze the disaccharide fucose, and as a result have severe neurological decline and die by age 6. The disease is due to a defect in the gene that encodes the lysosomal enzyme that breaks down fucose (α-1-fucosidase), and is inherited in an autosomal recessive manner. Jane and John have a child who has Type 1 fucosidosis. What is the probability that their next child will also have the disease? A. 4/4 or 100% B. No chance C. 3/4 D. 1/4
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