102. A 29-year-old woman who is an intravenous drug user is found to have increased serum AST and ALT activities. Immunologic testing shows positive results for hepatitis B surface antigenand total antibody to hepatitis B core antigen, and negative results for IgM antibody to hepatitis B core antigen. This patient will recover from this hepatitis B virus infection and be protectedfrom subsequent similar infections with this virus if she generates which of the following immune responses?A) Cytotoxic T-lymphocyte responseB) Production of neutralizing antibodiesC) Type II (complement-mediated cytotoxic) hypersensitivity responseD) Type III (immune complex-mediated) hypersensitivity responseE) Type IV (delayed) hypersensitivity response

Serum AST and ALT Activities: They are found primarily in liver cells. When liver cells are damaged,…

Answered: 102. A 29-year-old woman who is an…

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter17: Genes And The Immune System

Section: Chapter Questions

Problem 31QP

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44. Following a rattlesnake bite, a patient is injected with horse anti-rattlesnake venom, serum. Ten days later he has general weakness, muscular and joint pains. Laboratory studies show Proteinuria. Serum concentrations of immunoglobulins are within the reference range, but serum c3 and c4 qare decreased. Which is the most likely pathologic proces (A) Anaphylactic reaction (B) Delayed hypersensititvity to horse proteins (C) Formation of antigen-antibody complexes containing horse proteins and human immunoglobulins (D) Formation of antigen-antibody complexes containing snake venom proteins and horse antibody (E) Systemic reaction to snake venom
122. A 2-year-old boy has had recurrent episodes of otitis media and bacterial pneumonia. Serum immunoglobulin concentrations are: 1 mg/dL (N=23-190) 10 mg/dL (N=500-1300) 5 mg/dL (N=50-199) Further testing shows normal phagocytic function and delayed-type hypersensitivity responses. A lymph node biopsy specimen is most likely to show absence of which of the following cells? A) Capillary endothelial cells– IgA IgG IgM B) CD4+ T lymphocytes QC) CD8+ T lymphocytes OD) Dendritic cells E) Plasma cells
36) Autoantibodies associated with thrombosis in systemic lupus erythematosus are() A Anti-Sm antibody B Anti-SSA antibody C Anti-cardiolipin antibody D Anti-dsDNA antibody E Anti-nRNPantibody
88. A 19-year-old woman undergoes a PPD skin test prior to entering college. A 15-mm, firm area of induration is noted at the site 48 hours later. Which of the following is the most likely immunologic basis for this finding? A) Activation of CD4+ T lymphocytes B) Binding of IgG to the endothelium C) Complement activation by IgM D) Formation of immune complexes E) Release of histamine by mast cells
1) 286 individuals were newly diagnosed with Human Immunodeficiency Virus in 2018 in Minnesota. Of these individuals, 76% were male. HIV is an enveloped, ssRNA virus_ Baltimore classification VI. This virus targets CD4+ cells. CD4 refers to a glycoprotein which serves as a co-receptor for T-cells, located on T-helper and T-reg immune cells. a) What part of the HIV virus allows for specificity to CD4+ cells?
Differentiate the following secondary antibodies: (a) Mice anti-human, (b) Donkey anti-human, (c) Chicken anti-human, and (d) Donkey anti-chicken.
docs.google.com/forms/d/e/1FAlpQLSen_DnlxjlAa6EoAyAOhS Gitcmj9fQ_M4bwAg1Wizsq5Yp4A/formResponse O YouTube Maps nanswers TaT4 are rUC Which of the following are true regarding testosterone? * (1) Testosterone acts on specific target cells to stimulate male sexual characteristics. (2) Testosterone is directly stimulated by the release of GnRH. (3) Testosterone produces a negative feedback mechanism to regulate GnRH. (4) If spermatogenesis is slow, testosterone production is stimulated. O A- If answers (1), (2) and (3) are TRUE B- If answers (1) and (3) are TRUE O C- If answers (2) and (4) are TRUE O D- If only answer (4) is TRUE O E- If answers (1), (2), (3) and (4) are TRUE Which is true of the following statements regarding COVID-19? (1) SARS-CoV-2 is the virus that causes COVID-19 (2) The new coronavirus can infect the upper or lower part respiratorv svstem
2. https://doi.org/10.1186/s12868-022-00692-1 (link to research) a) In the immunohistochemistry section of the materials and methods section the authors wrote “The number of positive cells in hotspot areas in ten high power fields (HPFs) in areas of demyelination and plaques in the brain stem were counted using the image analysis software (Lecia Application Suite Version 4.12.0, Welzlar, Germany).” Why were they looking at demyelination areas for this study? b) In the effect of mitoxantrone on histopathological changes in the brain section of the results section the authors wrote “Active plaques revealed inflammatory cellular infiltrates with abundant macrophages stuffed with myelin debris, an evidence of ongoing myelin breakdown.” What does macrophages stuffed with myelin debris have to do with the study?
(56) A 1 year old boy dies of staphylococcal pneumonia. He has had multiple skin infections since birth. Separation of the umbilical cord was delayed. A skin window test was performed and no leukocyte accumulated on the cover ship. The cytometric analysis showed that only 5% of the T lymphocytes reacted with a monoclonal antibody to leukocyte functional antigen-1 chain (CD 18) compared with reactivity of 62 % for a normal subject. Just prior to death, his leukocyte count was 75,000/mm3. Which of the following is the most likely diagnosis? (A) AIDS (B) Cogenital Asplenia (C)Leukocyte Adhesion Deficiency (D) Severe Combined Immunodeficiency Disease (E) X linked agammaglobulinemia
A young adult is taking part in a hepatitis B vaccine phase III clinical trial. Her specific antibody titers are measured several days after each injection as part of the trial. She develops joint aches and swelling, as well as a slight rash, several hours after the third injection. After the study, an examination of her records reveals that she had high antibody titers after the first dose, with increasing titers with each subsequent dose. Which of the following is most likely to be the cause of her negative reaction?a. reaction to the vehicle (a substance in which the viral antigen is suspended).b. Anaphylaxis reactionc. Arthus-type hypersensitivity reactiond. production of antibodies cross-reacting with synovial (joint) antigens and epidermal antigens.
44. Which of the following is not true of the results of antigen-antibody binding? O Agglutination reducing the number of infectious particles to be phagocytosed Neutralization preventing toxins & viruses attaching to cellular receptors; and microbes from attaching via adhesins to mucosal surfaces Lysis (MAC), via activation by antibodies of all 5 immunoglobulin classes, of complement in the Classical pathway of complement activation, Antibody dependent cell-mediated cytotoxicity permitting natural killer (NK) cells to recognize & kill antibody coated cells; & eosinophils to attack worms with attached IgE. All of the above are true
(26) A laboratory animal is shceduled to be immunized by receiving 3 weekly injections of antigen X. After the last immunization, it is discovered that the preparation used for the final immunizaton was not purified to homogeinity and also contained antigen Y. Which of the following is the most likely to be the primary class of the antibodies to antigen Y in the blood drawn 2 days after the klast injection (A) IgA (B) IgD (C) IgE (D) IgG (E) IgM

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