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1. What is pharmaceutical dosage?
2. What is the contribution of pharmaceutical dosage to the field of pharmacy?
Step by step
Solved in 3 steps
- 1. If excipients do not have pharmacodynamic activity, how do excipients affect the performance of the drug product? 2. What is meant by the rate-limiting step in drug bioavailability from a solid oral drug product? 3. What is the usual rate-limiting step for a poorly soluble and highly permeable drug (BCS 2)? 4. How could the manufacturing process affect drug product performance? 5. Drug absorption involves at least three distinct steps: dissolution, permeation, and disposition during transit in GI (an additional step of drug disposition in the body is involved as well for bioavailability). How are these processes validated in vitro when the in vivo requirement for drug bioavailability is waived? 6. What is meant by “sink” conditions? 7. What physical or chemical properties of a drug substance are important in designing a drug for (a) oral administration or (b) parenteral administration? 8. For a lipid-soluble drug that has very poor aqueous solubility, what strategies could be…5. What is a hospital formulary? What is its importance in the hospital pharmacy setting?15. (Drug Development) What is the major difference in regulatory requirements between the approval of a new API dosage form (NDA) and a generic dosage form (ANDA)?
- What is the contribution of pharmaceutical dosage to the field of pharmacy?Based on what you have studied in school, how do you believe the application of pharmacology (the pharmacokinetic and pharmacodynamic principles) optimizes drug development (please cite examples from drug FDA website and/or literature)?1. Explain the importance of solubility in drug product formulation. 2.
- 1. Relationship of Drug solubility & dissolution rate on Physico-Chemical Properties 2. Relationship of Particle size & effective surface area on Physico-Chemical PropertiesName some pharmacology math conventions that have been instituted to keep patients safer.Discuss the effects of glass packaging materials on pharmaceutical dosage form? Discuss at your own words
- What impact does compounding have in pharmacy? Describe how compounding can improve medication compliance.The cost of pharmaceuticals to patients is consistently a significant concern. What are the primary drivers of the cost of developing new pharmaceuticals?What is the importance of chirality in drug development and marketing?