Answered: 1. Answer ALL parts. a) Detail how you…

1. Answer ALL parts. a) Detail how you would use the amidomalonate synthesis to prepare a racemic mixture of leucine. Include in vour answer a mechanism for the reaction.

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter21: Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions

Section21.SE: Something Extra

Problem 35MP

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Concept explainers

Amines

Amines are organic compounds with a nitrogen atom having a lone pair of electrons on it. They are derived from ammonia (NH3) wherein hydrogen atoms are substituted by an aryl or alkyl group.

Question

AMINO ACIDS AND PEPTIDES
1. Answer ALL parts.
a) Detail how you would use the amidomalonate synthesis to prepare a racemic mixture of
leucine. Include in your answer a mechanism for the reaction.

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