1 - How is the term "OPIOID" commonly related too? 2 - What types of OPIOID exist? Give an example for each. 3 - What are some effects of opioid use and why does this happen?
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- 1. Briefly differentiate the 3 opioid receptor subtypes. 2. Briefly differentiate the 3 hypotheses for the development of opioid tolerance and dependence. 3. Briefly differentiate the use of naloxone and naltrexone in opioid overdose and treatment programs.Which of the following are true statements? [Select all that apply.] The financial success of OxyContin is in large part due to aggressive marketing by its manufacturer. Opioid drugs are much safer than most prescription drugs. There is strong evidence to support the use of opioids for chronic noncancer pain. Abuse of opioid drugs presents a serious public health problem.REVIE W QU ES TION S 1. What is the mechanism of action of the benzodiazepines? 5. Which of the following drugs is/are metabolized to a compound that will continue to have significant sedative and hypnotic effect? 2. What is the mechanism by which antipsychotics work? 3. What pharmacokinetic properties are shared by most of the antipsychotic drugs? H3Ç 4. Which benzodiazepines shown below is/are short acting? CI H3C 1. Oxazepam 2. Temazepam H3C. F OH CI 1 CI H3C. CF3 3. Lorazepam 4. Midazolam H3C CI 3 4 5. Diazepam
- Why do people use crack cocaine? What are the major toxicity caused by the use of high doses of this stimulant?there's been several ideas for newer opioid medications that may reduce abuse liability, is there any new medications being developed that would be more difficult to abuse that can help abusers of opioids?1. What is the medical science concerned with the use of drugs in the treatment of disease? * a Pharmacotherapeutics b Pharmacology c Pharmacoepidemiology Pharmacognosy d Pharmacogenetics 2 Which of the following is ACCURATE about Reboxetine? * a MAO inhibitor b Noradrenaline reuptake inhibitor c Adrenergic agonist d Cholinergic agonist e Selective serotonin reuptake inhibitor 3 In Graded Dose-Response, which of the following parameters refers to the dose producing 50% of the maximum response? * a Potency b LD50 c Efficacy d Ceiling dose e ED50 4 Which of the following statements best describe a partial agonist? * a Interacts with more than one receptor type b Blocks the effect of the antagonist c Cannot produce the full effect even at high doses d Has low potency but high efficacy. e Has affinity but lacks efficacy 5 Which drug promotes transient muscle fasciculation followed by muscle paralysis that is not reversed by Neostigmine? * a Hyoscyamine b Rocuronium c Succinylcholine d…
- Fill in the table: S.No. Drug Sources Receptors where they Effect on the body on consumption bind 1 Opioids 2 Cannabinoids Cocaine 4 Alkaloids/ Nicotine Alcohol 6 Narcotic/ anabolic steroids 3.1.) How can these physiological factors listed below affect drug effects? Explain each. - diurnal rhythm - acid-base balance - hydration - electrolyte balanceAmong the over-the-counter painkillers available at a pharmacy, there is one substance that stands out, paracetamol. How is it different in terms of effect (s)? Also indicate what is the most serious side effect of an overdose of paracetamol.
- Pls explain in detail how the drug affected brain cells at the cellular or molecular level (do not just copy and paste on internet) Please write the details of each one. i need a long explanation each one. thanks 1. Heroin 2. Ecstasy 3. Cocaine 4.LSD5. Which of the following drugs is/are metabolized to a compound that will continue to have significant sedative and hypnotic effect? H3C OH -OH CI CI 1. Oxazepam 2. Temazepam H3C HO- 3. Lorazepam 4. Midazolam H3C 5. DiazepamBriefly describe the pharmacology of hallucinogenic drugs including: 1-pcp 2-LSD 3- Ketamine 4- dextromethorphan 5- MDMA 6-psilocybin