URGENT Question 100H₂N-CHC-OHCH₂NHCHN0A0HẠN–CHC-OCH₂NHHNtvBHẲNCH CAOCH₂NAHNWhat is the net charge of histidine at pH=pKa2?(pKal = 1.8, pKa2 = 6.0, pKa3 = 9.3).C0HẠN–CHC-O-CH₂MacBook ProG Search or type URLHN-No new data to save. Last checked at 6:45pmD☆17S

pKa is the pH at which half of the acid is dissociated. Given to us is the amino acid histidine with…

Answered: 0 H₂N-CHC-OH CH₂ HN A NH* 0 HẲN-CHC-O…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question 25 Calculate the net charges of the following peptides at pH 7.4. Indicate which amino acids bear chuarged side chans a) NH2-Asp-Leu-Phe-Ala-Lys-Pro-Glu-Gly-COOH b) NH2-GIn-Glu-Lys-Tyr-Trp-Arg-Ala-Leu-COOH DELL
Multisubunit proteins in which some or all of the subunitsare identical are referred to as _______________________.
Question 4. Imagine the main chain of a protein bends back on itself so that two amino acid residues R1 and R2 come close to each other. In the table below are four possibilities for what R1 and R2 might be. In each case, decide whether a specific interaction could form between the residues. If a specific interaction could form, give the name of the interaction. R₁ cysteine tyrosine threonine arginine R₂ cysteine phenylalanine glutamine aspartate specific interaction? OO yes O yes O no no OO O yes no yes no name of specific interaction 0 П 0 0
Question 11. // Hint: Isoelectric focusing separates proteins based on their pI values, and can separate proteins that only differ by a net charge of ±1.±1. Recall that an amino acid residue with a negatively charged R group has a relatively low isoelectric point (pI) where it has zero net charge. Likewise, an amino acid residue with a positively charged R group has a relatively high isoelectric point (pI) where it has zero net charge. Order from Low pH to High pH
Question 1.)Draw the main chain structure of a parallel beta sheet that has 4 amino acids in one strand and 5 in the other. Show all of the backbone atoms.Write R1, R2, R3, etc, instead of drawing side chains with the following exception: draw one proline in its entiretywith its side chain. You can put it anywhere in your sheet – I will find it. Add in all hydrogen bonds that stabilize this sheet using dashed lines.
Question 7: Peptide nucleic acids (PNAS) exhibit greater stability as heteroduplexes with DNA (ie PNA-DNA duplex) than does double-stranded DNA (i.e. DNA-DNA duplex). However, peptide nucleic acids lack charged groups, making them largely insoluble under near-physiological conditions in aqueous buffer. Provide (1) an explanation for the increased stability of PNA-DNA duplexes (hint: consider intermolecular forces). (2) Additionally, propose modification(s) of the PNA scaffold DNA that could increase solubility without drastically reducing duplex stability. PNA R1 HN но. Base Base o=P-O NH Base Base 8 o=P-O- NH 8. Base Base НО NH
The _____________ is the term used for polypeptide destruction motifs.
QUESTION 10 Select all of the true statements regarding the molecule below: NH, -P-O NH G OH NH, О-Р-О- H,N N- A ОН -P-O `NH U ОН 0-P-O- N' ОН ОН This is RNA This is DNA This chain is a polymer. The backbone of these nucleotides is a ribose sugar This nucleic acid is the hereditary material for humans. This nucleic acid is the hereditary material for coronaviruses. This type of nucleic acid is never found in healthy human cells. This nucleic acid contains the nucleobase thymine.
Cells in the human liver contain glycogen, a polysaccharide that is used as a source of energy. This is a model of a typical glycogen granule: 42 22 AWARD Edit View Insert Format Tools Table be *** www 27544 Hals De w Jay MASCH Abh P CON p bo H S ******** 124 3. P WH ** patink The G k page flees P ******* 44651 CAPE Porn Tele de to MATE www 74 H Supe This type of granule may contain up to 30,000 (3 x 104) glucose subunits, making up the glycogen chains. A. How many ATP's could theoretically be produced when a granule of glycogen is hydrolyzed to glucose subunits that then enter glycolysis and respiration? B. Glycogen metabolism is regulated by insulin and glucagon. Both of these hormones are produced by the pancreas and act as signals that interact with a transmembrane receptor on target cells. Intracellular events involve protein kinase A that activates or inactivates enzymes involved in glycogen synthesis or degradation. Briefly describe what protein kinase A does to these proteins.
Question: 1. Identify the amino acids in this peptide 2. Which amino acid sidechains are protonated at physiological pH 3. What is the overall charge of this peptide H₂N O NH₂ IZ ZI O OH IZ OH OH
52.16 I'm not sure how I'm getting these wrong.
Normal hemoglobin (HbA) leu thr pro glu glu lys Sickle cell hemoglobin (HbS) leu thr pro val glu lys ser What is the difference between sickle- cell amino acid sequence and normal amino acid sequence?

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0 H₂N-CHC-OH CH₂ HN A NH* 0 HẲN-CHC-O CH₂ HN B NH* HÌN CHỈO HẠN CHÈO CH₂ CH₂ N N HN- C HN D What is the net charge of histidine at pH=pK₂2?(pKal = 1.8, pKa2 = 6.0, pK₁3 = 9.3).