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The Immediate Responsiveness Of Conditioned Pain Modulation

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The purpose of the study is to assess the immediate responsiveness of conditioned pain modulation (CPM; formerly known as diffuse noxious inhibition control or DNIC) as an outcome variable and its association with neck pain and global rating of change (GROC) in neck function among chronic neck pain sufferers between the 1st to 5th years from the onset of condition. Chronic neck pain is largely non-specific in nature and requires a biopsychosocial understanding of risk factors to mitigate their poor outcome. Practice guidelines highlight the importance of classifying these patients, which includes a biopsychosocial perspective for effective intervention (Cote et al 2016). Recent evidence also points to the success of personalized pain management that is anchored on specific neurophysiologic mechanism underpinning the pain experience of each individual (Nir and Yartniksy 2015). There is emerging evidence that simultaneously evaluating this neurophysiologic mechanism, along with biopsychosocial variables identified risk factors related to the development of chronic neck pain at one year (Shahidi et al 2015). There is extensive literature on pain and function outcome variables relating to biopsychosocial factors. In the past few years, there is growing evidence in the neurophysiologic mechanisms literature that includes CPM/DNIC’s validity and reliability in various chronic pain states. There is a call for CPM/DNIC to be used as outcome variable because it signifies the status

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