The Disease Of Alzheimer 's Disease

When it comes to Alzheimer’s, I know firsthand how it affects individuals and their families. My great grandfather had Alzheimer’s for many years before his passing late last year, at age 92. Alzheimer’s is a disease that many individuals suffer with each year, but yet with all the advancements in modern medicine we still have no cure for it. There are different ways to conquer this disease, understanding the causes, knowing effects, and researching possible treatments.

Alzheimer 's disease (AD) is a progressive degenerative disease of the brain from which there is no recovery. There are three brain abnormalities that are the hallmarks of the Alzheimer’s disease is initially caused by plaques buildup in the brain’s neurons as illustrated in figure 1. The support structure that allows the flow of the nutrients through the neurons gets damaged and ultimately there is loss of connection among the neurons and they die off (National Institute of Health, 2015). This causes the brain tissue to shrinks, which is called atrophies. All this ultimately lead the victim of this disease to face difficulties in governing emotions, recognize errors and patterns, coordinate movement, and remember. Ultimately, a person with AD loses all memory and mental functioning.

The disease stem cells could fix is called Alzheimer’s Disease (AD). The reason I chose this topic is because I have seen first hand how badly someone who suffers from Alzheimer’s Disease is affected in their daily lives. This disease completely takes over their lives and they turn into a completely different person who can hardly function. AD is very tough on the loved ones of the person suffering from it because that person, most of the time has no idea what is going on or who their loved ones are. The memories for people with AD is completely gone and even the simplest tasks such as remembering to use the bathroom becomes difficult. The way stem cells could be feasible is because stem cell-based therapies could potentially treat

Alzheimer’s disease in many ways is not yet defined. It is a progressive disease afflicting between 5 and 15 percent of people over 65. Additionally, it is not restricted to the elderly, reportedly having

Alzheimer’s is a disease in the brain that affects a person’s memory, thinking, and behavior. It is the most common form of dementia and is common in adults older than 65. More than five million Americans are being affected by Alzheimer’s at this moment. Alzheimer’s comes in three stages; early, middle, and advanced. The disease is caused by the shrinking of the brain due to many risk factors and genetics.

Dementia can be defined as a decline in mental ability severe enough to interfere with daily life (alz.org). More than often, individuals affected by dementia are over the age of 65. In the United States, there are more than three million cases of dementia each year. According to World Health Organization, the number of people living with dementia is currently estimated at 47.5 million worldwide and is expected to increase to 75.6 million by 2030 (World Health Organization 2015). Dementia is caused by physical modifications in the brain and is known for loss of memory and mental abilities. It’s a progressive disease which means it gets worse over time. If diagnosed early on, the quality of life for people with dementia as well as their family members can be significantly improved. There are many different types of dementias although some are far more reciprocal than others. One of the most common types of dementia is Alzheimer’s disease. Other few types of dementias are “Vascular dementia, Mixed dementia, Parkinson 's disease and Frontotemporal dementia (Krishnan, D. S)”. All of the various forms of dementia tend to have similar symptoms which consequently makes it hard to determine the type of dementia a patient may be suffering from.

Alzheimer’s Disease has been one of the top leading causes of death in our country. It is understood that this disease is identified as an excess of the protein amyloid-ß within an increase of plaque (Seneff, Wainwright, and Mascitelli, 2010). Additionally, as the brain ages, it gets used to the inflammation and oxidative stress, so it is important to take the right amount of antioxidant micronutrients like vitamin C and vitamin E as well as anti-inflammatory macronutrients such as omega-3 polyunsaturated fatty acids to protect the brain from ageing (Whalley et. al, 2004). This is a devastating disease that affects most people over the age of fifty. Recently, there have been many studies done to figure out what causes this disease, if there is anything that can cure it, and how to prevent the disease. Seneff, Wainwright, and Mascitelli, believe Alzheimer’s develops with consuming too many carbohydrates, especially fructose and having a deficiency in cholesterol and dietary fats as well (2010). Whalley, Starr, and Deary have seen that poor diet, poverty, and failing health are links to developing Alzheimer’s Disease (2004). Furthermore, seeing increase in plasma homocysteine concentration increases risk of Dementia, which can result from an inadequate intake of vitamin B12/folate (Walley et. al, 2004). Additionally, Gray supports Walley’s findings and even believes having an adequate intake of vitamin B12/folate will have a positive effect on the overall health

Alzheimer’s disease is a prominent brain disease that effects a massive amount of individuals in the United States. Alzheimer’s disease (AD) is the sixth leading cause of death in the United States, accounting for 60-80% of dementia cases, with no chance of being cured, prevented or decelerating over time (Alzheimer’s Association, 2014). AD is the most well-known form of dementia, causing complications in brain function in the areas of memory, thinking, and behavior (Alzheimer’s Association, 2014). In an effort to gain a deeper understanding of Alzheimer’s disease, researchers create new knowledge about the disease, which is then distributed to the public. The goal in this information disbursement is to find new and inventive ways to treat AD, prevent AD from progressing at such a rapid pace, and aid in the quality of life in those diagnosed with AD as well as caregivers and medical professionals providing treatment to individuals’ with AD.

Alzheimer’s disease is a complex illness that affects the brain tissue directly and undergoes gradual memory and behavioral changes which makes it difficult to diagnose. It is known to be the most common form of dementia and is irreversible. Over four million older Americans have Alzheimer’s, and that number is expected to triple in the next twenty years as more people live into their eighties and nineties. (Johnson, 1989). There is still no cure for Alzheimer’s but throughout the past few years a lot of progress has been made.

“There is one thing Alzheimer 's cannot take away, and that is love. Love is not a memory - it 's a feeling that resides in your heart and soul.” (Fade to Blank). The human brain is a remarkably complex organ that processes, stores, and recalls information. “Alzheimer 's disease (AD) is a slowly progressive disease of the brain that is characterized by impairment of memory and eventually by disturbances in reasoning, planning, language, and perception. Many scientists believe that Alzheimer 's disease results from an increase in the production or accumulation of a specific protein (beta-amyloid protein) in the brain that leads to nerve cell death.” (Crystal). It is the most common form of dementia, accounting for 50 to 80 percent of dementia cases, and currently has no cure. (# 3) Research continues to be done to develop better ways to care for those affected with the disease, as well as to find support for family members, friends, and caregivers. Alzheimer’s is a devastating illness that is not a normal part of aging. In order to find a cure, awareness needs to increase to improve understanding, develop effective treatments, and to essentially prevent the disease.

     It is inevitable that eventually each of us will grow old and begin to face more and more health problems as our age rises. Elderly people are challenged by many illnesses and diseases that unfortunately, are incurable. One disease that becomes more common as people age is Alzheimer’s disease. Alzheimer’s a common cause and a form of dementia and can severely damage a patient’s cognitive functions and can ultimately cause death. Living with Alzheimer’s disease can be saddening for both the sufferer and the family. Family and friends will find it very hard to cope when a loved one begins slipping away and losing memory of who they are.

Alzheimer’s dementia is a prototypical neurodegenerative disease characterized by a series of abnormalities in the brain that selectively affect neurons in specific regions. There is a progressive decrease in neuronal activity and neuronal survival. Historically, researchers have used Magnetic Resonance Imaging (MRI) technology to scan patients with Alzheimer’s disease and the normal elderly. Using supercomputers, color-coded maps were created that revealed the degenerative sequence of Alzheimer’s disease via novel brain mapping methods. These brain maps showed a wave of gray matter loss that was strongly related to the progressive decline in cognitive functioning which is a key feature of the disease. The Alzheimer’s patients lost an average

Many tend to get dementia and Alzheimer’s confused, but they are two different diseases. People with dementia have symptoms that can vary greatly such as memory loss, communication and language, ability to focus and pay attention, reasoning and judgement, and visual perception. There are 36 million people estimated to live with dementia, and this number is rapidly increasing” (Alzheimer’s Disease International, 2012). When someone has dementia, it starts off slowly but then progresses quickly. “Dementia is a chronic or persistent disorder of the mental processes caused by brain disease or injury and

Alzheimer’s disease is one of the most devastating diseases affecting approximately 5.3 million people in the U.S. (Alzheimer’s Association, 2015; Caminiti, 2015; Hammer, 2016). It is not exclusively a disease of old age as over 200,000 are diagnosed under the age of 65. Other startling facts are that a majority of afflicted by Alzheimer’s are women and the rates of diagnosis are increasing substantially (Alzheimer’s association, 2015). Alzheimer’s is a complicated disease that robs a person of their memory and eventually their bodily functions, rendering the person unable to care for him or herself. Furthermore, Alzheimer’s is fatal with no cure or prevention known to this date. There has been a 71 percent increase in Alzheimer’s deaths compared to other major deadly diseases during the first 13 years of this century.

Alzheimer is a disease that affects the elderly most. The disease was discovered by Dr. Alois Alzheimer in the year 1906 when he was examining a female’s brain. He found out that the woman displayed memory loss, language problems and some inexplicable changes in behavior. The disease was named after the doctor who was a German psychiatrist and a neuropathologist. Alzheimer’s disease is a degenerative brain disorder that leads to memory loss, personality changes, and language problems (Gilbert & Julie 2). The disease is mostly diagnosed in people over the age of 65 years, though there is a small minority of people under the age of 50 who get the disease. Studies show that 1% of a whole population aged between the ages 65-75 have severe