STEM CELLS WORKING TO SPECIALIZE INTO CARDIAC CELLS
Once the stem cells are delivered near the damaged areas of the heart, the regeneration of cardiac (heart) cells is possible. There is a lack of understanding on how or why specifically the stem cells turn into heart cells. “Recent studies indicated that the benefits associated with adult stem cell injection might come from paracrine effects, the effect of a nearby cell sending chemical and electrical signals to the stem cell, and not from myocardial differentiation” [6]. Experiments show that bone marrow stem cells “produce and secrete a broad variety of cytokines, chemokines, and growth factors, [all of which] promote cardiac repair [7]. These paracrine factors “influence adjacent cells and exert their actions” on the damaged cardiac cells [7]. It might be that the stem cells do not even differentiate into cardiac cells, but instead promote repair through exchanges of signals. “Recent work suggests that coupling of myocytes to adjacent cells, tissues, and extra cellular matrix results in external cues that shape ventricular myocytes architecture” [8]. Basically, the surrounding heart cells connect with the stem cells to essentially form the shape of the original area of the heart. The cells “wrap around the ventricular cavities in the developed heart” [8]. The many therapies discussed in the previous section “assume that transplanted cells will support…ability for differentiation and functional integration into the host
Many of us have all heard the saying that a “lizard can lose its tail,” and bizarrely enough it will grow back. This was always considered impossible for humans, an idea belonging in the realm of science fiction, but now the regeneration of tissue is an extremely realistic possibility. Despite some opinions, this process does not happen naturally, or take place as cinematically as one might imagine. Over the past decade, there have been major advances in regenerative medicine, commonly known as stem cell research. Stem cells are undifferentiated cells within the body that have the capability to specialize into any tissue. They are most commonly found in cord blood, bone marrow, organ donations, placenta, and embryos . Stem cells are seen by some as a new miracle treatment, encouraging many countries to invest in their research.
Thesis: Stem cell research is a great example for the controversial uprisings by advances in bio-medical research. There are many different pros and cons when it comes to discussing the use of stem cells. In order to develop an opinion of whether or not stem cells should be used, one must first understand what they are and how they are used. Moreover, I will point out how stem cell research is beneficial in today's society.
In preparation for this thesis on the topic of stem research and application; I gathered data through various methods to reach a broad consensus on the public impression of stem cell research. In this chapter I will discuss the findings of those ventures and the impressions it made on my research. I conducted a survey asking general information on the public’s knowledge of stem cell research and held a classroom forum asking for open opinions on research.
Christopher Reeve, better known as superman, was not only an actor, but also an athlete and an adventurer. On two separate occasions, he flew an airplane sole across the Atlantic Ocean. On Memorial Day weekend in 1995, Chris rode his horse, Buck, to the starting box of a cross-country race in Virginia. Chris had trained and raced horses for almost ten years, so he felt the course ahead of him would be easy. But what Chris did not see coming was just as he and Buck approached the third jump, Buck would come to a sudden stop, sending Chris over the jump. He landed directing on his head, fracturing two vertebrae in his neck. From that day on, he was completely paralyzed. At the time, there was no known treatment, no medication, and no surgery to fix his damaged spine. For the rest of his days, Chris raised money and awareness for research into spinal cord injuries. One of the topics he pushed for was embryonic stem cell research. Christopher Reeve died on October 10th, 2004, never fulfilling his goal to walk again. But if he had gotten the support and funding for stem cell research, his story might have ended differently. Embryonic stem cell research should be funded in the U.S because it could lead to the treatment to many diseases, there are other sources of stem cells, but they are limited to their use, and the eight-celled blastocysts cannot grow any further to form a baby, so it is not harming living human beings.
Stem cells are cells that are found throughout the human body. They reproduce over a long period of time without changing. Stem cells can produce specialized cells, such as brain, muscle or lung cells. Stem cells in the last few years have recently made a big debut because medical professionals have discovered so many unique qualities to stem cells. They are on the cutting edge of medicine because of all their uses and the qualities that make them so unique from any other cell in the body. Stem cells have the power to make so many breakthroughs in the medical world. Medical researchers have all ready found so many ways that stem cells can be used for the better of so many people. Genes play an important role in determining what genetic traits or mutations we receive. Researching stem cells can help determine this. Stem cell research is useful for learning many things about human development and about how the body has the power to repair itself. Researchers are finding new ways each day that stem cells can be used and the possibilities that they find for stem cells could be endless. A few ways they can be used to treat diseases, be used as graphs for burn victims or surgical use, and even to correct birth defects. The pros of stem cells are limitless.
With exponential increases in the capabilities of modern technology, it only fits that we use this technology to further our existence as a species. Embryonic Stem Cell Research is one of the ways we have come up with to advance our species into the future. However, the perpetrators and supporters have been under fire and controversy since its inception in 1979. The protesters are fighting it mainly because it is destroying unborn fetuses in the process.Personally, I have a special and specific connection to embryonic stem cell research. As a Type 1 Diabetic, I know that the Juvenile Diabetes Research Foundation uses embryonic stem cell research in its efforts to find a cure for Type 1 Diabetes. The main use for the stem cells they have is
In Brazil 2009, there was an 18 year old boy that had half of his jaw and teeth removed because of a tumor. Scientists took some of his bone marrow and extracted the adult stem cells from it and formed an osteoblast, which is a bone forming cell. Six months after the osteoblast was injected, it started forming new bone material which filled the gaps (NIH Stem Cells). Stem cells could be a genius way to treat many diseases and disorders and it should be supported by everyone.
Stem Cell Research: Should we continue to allow scientists to create new embryonic stem cell lines?
Stem cells are cells with the potential to become any type of cell in the body. There are two different types of stem cells: adult stem cells and embryonic stem cells. Adult stem cells are very valuable and are used mainly to treat blood diseases, but sometimes adult stem cells from the brain are used to treat neurological diseases. Adult stem cells can also be difficult to recognize in the adult body. Embryonic stem cells are more flexible than adult stem cells and can be used for a bigger variety of diseases (California’s Stem Cell Agency,2011). Some people do not believe in the use of embryonic stem cells, because they believe they are killing future life. Despite the controversy over how stem cells are gathered, stem cells have undeniable
After patients have gone through heart disease, like any other injury, therapeutic steps must be taken. Therapy and rehabilitation of damaged hearts has been improved through the utilization of stem cells. Therapy includes strengthening of the damaged area as to prevent the incident from reoccurring and getting the patient back to their normal life. Scientists, again, used rats that had had induced myocardial infarctions. This
Many controversial and moral stricken issues have been put into question in today's modern society. Some of which include gay marriage, and abortion. Yet one of the most controversial has to be stem cell research. A Stem Cell is a "generic" cell that can make exact copies of itself indefinitely. It also has the ability to make specialized cells for various tissues in the body such as the heart muscle, brain and liver. But why exactly is stem cell research so controversial? Well mostly those who oppose embryonic stem cell research do so on the grounds that the cells die in the process. But what those people might not know is that an embryo is no bigger than a pinhead. And therefore there is no human suffering. Stem cell
Stem cells have an interesting history that has been linked with debate and controversy whenever it is brought up in a conversation in today's society. However, most people do not know the reasoning behind stem cell testing or using them to benefit society. It all started in the mid 1800s, stem cells were discovered as the cells that were the "building blocks of all the other cells." They serve as the body's own repair system. Stem cells can be vary in size, how they are obtained, and their benefits, they can help solve problems of an everyday human being, and can possibly find a cure for some of the most heartbreaking diseases on the planet.
Stem cells are cells within the body that have the ability to grow and reproduce repeatedly into any type of mature cell. They are unspecialized cells that divide through mitosis to produce more stem cells that replace cells in the system in which they are found. Stems cells make it possible for the body to renew and repair its damaged tissues. They are also vital in the development of human life. Stem cells are high potential cells, and this makes them a top focus in the biomedical research world. (Stem Cell Basics, 2009) This paper will discuss the background, function, and other aspects of stem cells.
A Stem Cell is a similar cell to a multicellular organism. That organism has the ability make an infinite amount of the same type cells.
1) How are stem cells different from normal cells? Why are these differences important for medical research?