Topic 2 DQ 1 SR 2

.docx

School

Grand Canyon University *

*We aren’t endorsed by this school

Course

641

Subject

Psychology

Date

May 6, 2024

Type

docx

Pages

Uploaded by AgentToad4373 on coursehero.com

1 Topic 2 DQ 1 SR 22 Paige Martin Haloperidol (Haldol) Haloperidol is a first-generation typical anti-psychotic used to manage positive symptoms of schizophrenia, including hallucinations and delusions (Rahman & Marwaha, 2023). Haloperidol is approved by the U.S. Food and Drug Administration (FDA) for a variety of clinical applications including schizophrenia, Tourette syndrome, and severe behavioral disorders in children (impulsivity, attention difficulties, aggressiveness, and low frustration tolerance) (Rahman & Marwaha, 2023). There are also off-label uses of haloperidol Including: acute mania, chemotherapy-induced nausea and vomiting, and managing hiccups. Absorption: Haloperidol is a highly lipophilic drug that undergoes extensive metabolism, which leads to variability in its pharmokinetics In individuals. Oral formulation peaks around 2-6 hours after administration and 20 minutes after IM administration. Distribution: About 89%-93% of the drug binds to plasma proteins and the concentration in the brain is significantly higher than in the serum concentration. Metabolism: It is metabolized in the liver through sulfoxidation and oxidation pathways, and involves CYP3A4, CYP2D6, and a little of CYP1A2 enzymes. Excretion: Thirty percent of the drug is excreted in the urine. and the genetic polymorphism of CYP2D6 influences the plasma concentration of the drug. Haloperidol is not recommended in older adults as there is an increased risk of stroke and greater rate of cognitive decline. According to the American Geriatrics Society Beers Criteria Expert Panel (2023), there is an increaed risk of anti-psychotic medication and mortality

2 Independent of dementia. It is suggested to avoid this medication in older adults, except in FDA approved uses. I have administered this medication to older adults when they are combative and confused and I get varying effects. Sometimes it works well and the patient calms down, other times, the patient gets even more agitated. I definitely think it depends on the dose as well. I did just administer this medication to a patient last week as he was becoming combative and threatening to leave the hospital (psych said he lacked capacity) and we did our best to distract him and talk him down but we ultimately had to administer haldol to calm him down. References: By the 2023 American Geriatrics Society Beers Criteria Update Expert Panel. (2023). American geriatrics society 2023 updated AGS Beers Criteria for potentially inappropriate medication use in older adults. Journal of the American Geriatrics Society, 71(7). https://doi.org/10.1111/jgs.18372 Rahman, S. & Marwaha, R. (2023). Haloperidol. StatPearls [Internet]. https://www.ncbi.nlm.nih.gov/books/NBK56089

Your preview ends here

Eager to read complete document? Join bartleby learn and gain access to the full version

Access to all documents
Unlimited textbook solutions
24/7 expert homework help

Recommended textbooks for you

Ciccarelli: Psychology_5 (5th Edition)

Psychology

ISBN:9780134477961

Author:Saundra K. Ciccarelli, J. Noland White

Publisher:PEARSON

Cognitive Psychology

Psychology

ISBN:9781337408271

Author:Goldstein, E. Bruce.

Publisher:Cengage Learning,

Introduction to Psychology: Gateways to Mind and ...

Psychology

ISBN:9781337565691

Author:Dennis Coon, John O. Mitterer, Tanya S. Martini

Publisher:Cengage Learning

Psychology in Your Life (Second Edition)

Psychology

ISBN:9780393265156

Author:Sarah Grison, Michael Gazzaniga

Publisher:W. W. Norton & Company

Cognitive Psychology: Connecting Mind, Research a...

Psychology

ISBN:9781285763880

Author:E. Bruce Goldstein

Publisher:Cengage Learning

Theories of Personality (MindTap Course List)

Psychology

ISBN:9781305652958

Author:Duane P. Schultz, Sydney Ellen Schultz

Publisher:Cengage Learning

SEE MORE TEXTBOOKS

Recommended textbooks for you

Ciccarelli: Psychology_5 (5th Edition)
Psychology
ISBN:9780134477961
Author:Saundra K. Ciccarelli, J. Noland White
Publisher:PEARSON
Cognitive Psychology
Psychology
ISBN:9781337408271
Author:Goldstein, E. Bruce.
Publisher:Cengage Learning,
Introduction to Psychology: Gateways to Mind and ...
Psychology
ISBN:9781337565691
Author:Dennis Coon, John O. Mitterer, Tanya S. Martini
Publisher:Cengage Learning
Psychology in Your Life (Second Edition)
Psychology
ISBN:9780393265156
Author:Sarah Grison, Michael Gazzaniga
Publisher:W. W. Norton & Company
Cognitive Psychology: Connecting Mind, Research a...
Psychology
ISBN:9781285763880
Author:E. Bruce Goldstein
Publisher:Cengage Learning
Theories of Personality (MindTap Course List)
Psychology
ISBN:9781305652958
Author:Duane P. Schultz, Sydney Ellen Schultz
Publisher:Cengage Learning