E. Cobham Brewer 18101897. Dictionary of Phrase and Fable. 1898.
Make a hand of or on (To).
To slay, destroy, waste, or spoil.
So when I came to myself again, I cried him mercy; but he said, I know not to show mercy; and with that knockt me down again. He had, doubtless, made a hand of me, but that one came by, and bid him forbear.Bunyan: Pilgrims Progress, p. 93 (first edition).