You insert a gene (GFP) that produces a green fluorescence signal into several single- celled zygotes of frogs. The GFP gene can only insert once into the genome at a random location. In screening the fully-developed genetically-engineered frogs you observe three different patterns of green fluorescence. a. Most frogs fluoresce throughout their entire body b. Some frogs fluoresce only in their muscular tissue c. Few frogs do not fluoresce anywhere despite having the GFP gene sequence in their genome Explain what likely happened in each of these cases

Biomedical Instrumentation Systems
1st Edition
ISBN:9781133478294
Author:Chatterjee
Publisher:Chatterjee
Chapter15: Instrumentation In Medical Imaging
Section: Chapter Questions
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You insert a gene (GFP) that produces a green fluorescence signal into several single-
celled zygotes of frogs. The GFP gene can only insert once into the genome at a
random location. In screening the fully-developed genetically-engineered frogs you
observe three different patterns of green fluorescence.
a. Most frogs fluoresce throughout their entire body
b. Some frogs fluoresce only in their muscular tissue
c. Few frogs do not fluoresce anywhere despite having the GFP gene sequence in
their genome
Explain what likely happened in each of these cases

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