Why are restriction endonucleases considered a bacteria’s “innate immune system”? Why is CRISPR-Cas9 considered a bacteria’s “adaptive immune system”? What does CRISPR stand for?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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  1. Why are restriction endonucleases considered a bacteria’s “innate immune system”?

 

  1. Why is CRISPR-Cas9 considered a bacteria’s “adaptive immune system”?

 

  1. What does CRISPR stand for?

 

  1. What is the difference between crRNA and tracrRNA? Why are both needed for Cas9 to function?

 

  1. What does PAM stand for? Where is it found?

 

  1. What is the difference between Non-homologous End Joining (NHEJ) and Homology Directed Repair (HDR)?

                                                                                                              

  1. What is the Guide RNA (gRNA) a chimera of? Why use a gRNA?

 

  1. What new things are researchers doing with CRISPR-Cas9?

 

  1. Reflecting on what you now know about CRISPR-Cas9, what are your thoughts on it’s use in humans and other organisms? What should we be allowed to do? Not do?

 

  1. Are viruses living? Why or why not? What does obligate intracellular parasite mean?

 

  1. What does every virus have? What is the difference between capsomers and capsids?

 

  1. What is the difference between a naked and enveloped virus? What are the benefits and disadvantages of each? How does each enter and exit a host cell?

 

  1. What is the difference between host range and tissue tropism?

 

  1. What is the difference between “+strand RNA viruses” and “–strand RNA viruses”? What must every –strand RNA virus bring into the cell with it? Do +strand RNA viruses have to turn into –strand at any point in their replication?

 

 

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