what Protien ligand interacts the EPH RECEPTOR EPHB2 and what drug binds to the receptor. give example and Include details of bidning and signalling.
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what Protien ligand interacts the EPH RECEPTOR EPHB2 and what drug binds to the receptor.
give example and Include details of bidning and signalling.
Step by step
Solved in 2 steps
- Provide annotated structure image/diagram of the EPH RECEPTOR B2 (EPHB2). Giving the ligand bidning sites.Explain in detail the funcations and signalling of ephrin receptors. Provide examples.explain in detail ephrin receptor EPHB2 receptor interaction with PDZ ligand. give full step by step explanantion.
- Three potential inhibitors for VEGF were discussed in the signal transduction simulation. Explain two possible steps that these drugs can be expected to interfere with VEGF signaling (Hint: think about the requirements for signaling to occur).Give examples of two histamine antagonists that have very different tissue specificities and functions.Identify at least three key actions of epinephrine that render this agent beneficial for treating severe allergic reactions.
- example of EPH RECEPTOR EPHB2 ligabnds Give details of examplesname and describe the isoforms of the leptin receptor.In a breast cancer patient whose tumor cells express large amounts of estrogen receptors and are therefore very sensitive to estradiol, which of these drugs will be very effective in reducing plasma levels of estradiol and consequently the breast tumor growth? Group of answer choices Letrozole Paclitaxel Methotrexate Megestrol
- Explain EPHB2 receptor interaction with PDZ-binding. Give full explanantionName two second messengers of GPCRs and identify the type of GPCR each second messenger commonly associates with (Gs, Gi, Gq, G12/13, Go; there are many possible answers for this question).Describe the main mechanisms by which G proteins are activated upon norepinephrine binding