What is NOT true about the energetics of glycolysis and gluconeogenesis? O gluconeogenesis is inhibited during intense exercise O only energy releasing reactions will give a net yield of product O glycolysis has a net direct yield of two ATP's whereas gluconeogenesis uses 2 ATP's O in gluconeogenesis, glycolysis enzymes with a highly negative AG are replaced O a reaction must have a negative AG to proceed in the forward direction
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- Figure 27.3 illustrates the response of R (ATP-regenerating) and U (ATP-utilizing) enzymes to energy charge. a. Would hexokinase be an R enzyme or a U enzyme? Would glutamine: PRPP amidotransferase, the second enzyme in purine biosynthesis, be an R enzyme or a U enzyme? b. If energy charge = 0.5: Is the activity of hexokinase high or low? Is ribose-5-P pyrophosphokinase activity high or low? c. If energy charge = 0.95: Is the activity of hexokinase high or low? Is ribose-5-P pyrophosphokinase activity high or low?Question 8: The following table shows the glycolysis reactions and their standard Gibbs free energy changes at 25 C. Answer the following questions: A. What is the Gibbs free energy expression of the glycolysis pathway? B. What is the overall reaction of the glycolysis pathway? C. Suppose that the physiological concentrations of some metabolites are known as follows:C000 C000 NADH NAD -NADH NAD* oco, NAD Oco,- FADH NADH FAD ATP ADP+,P Select the conclusion that would most accurately explain the impact on the Krebs Cycle if glycolysi were to slow down its rate of reaction. ATP production would increase since glycolysis would be using less ATP. The Krebs cycle production of FADH2 would increase. O The Krebs cycle would continue to function at a normal rate. O The Krebs cycle production of NADH would decrease.
- Glycolysis and Krebs cycle pror TWGPalygXphYW9-zKh7Bt-bdNc75nprw176dBUWOA mResponse 23. Select the situation that will NOT happen if ATP synthase is not functioning. O A. Damage to the chemiosmosis process. B. The number of ATP produced is reduced. C. ATP can be produced through oxidative phosphorylation. D. Accumulation of proton ions in the intercellular membrane. 24. Oxidation of organic compounds that produced carbon dioxide, water and release of free energy causing reduction of the final acceptor molecule: oxygen. Justify the reason. ray bonds than those inWhich statement is FALSE concerning glycolysis? Group of answer choices It is activated by high [AMP]. It results in a net synthesis of ATP. It results in the synthesis of NAD+. None of the 11 intermediates in the glycolytic pathway are phosphorylated.Different enzymes that catalyse the same reaction are called O A. isoenzymes O B. holoenzymes O C. cofactors O D. coenzymes O E. agonists Which statement concerning the glycolytic and gluconeogenic pathways is correct? O A. Both are catabolic. O B. Both are anabolic. O C. Gluconeogenesis is catabolic while glycolysis is anabolic. O D. Gluconeogenesis is anabolic while glycolysis is catabolic. O E. Gluconeogenesis occurs in brain and glycolysis occurs in muscle. In lactic acid fermentation, which substance is oxidized and which is oxidized? O A. Lactate is reduced and NAD* is oxidized. OB. Lactate is reduced and pyruvate is oxidized. OC. Pyruvate is reduced and NADH is oxidized. O D. NADH is reduced and pyruvate is oxidized. O E. Lactate is oxidized and NADH is reduced.
- ATP and NADH are the ------ of-3 * aerobic glycolysis Non of the above O Activators Inhibitors All of the above OMatch group A with group B: Group A Group B ATP synthase that makes ATP, is a Pyruvate part of Transfers the electrons from cyt c to O2 NADH Both glycogen synthesis and glycogen +NAD breakdown share the metabolite Glucose converted into two of these ТСА суcle molecules a-ketoglutarate dehydrogenase ETC inhibited by The central catabolic pathway is Ubiquinone Cytochrome c oxidase Glucose-1- phosphateWhat is the main enzyme that serves as the control point in the regulation of glycolysis? Hexokinase O Phosphoglyceromutase O Pyruvate kinase O Phosphofructokinase O Isomerase
- This figure depicts the energy investment phase of glycolysis. Enzymes catalyzing the reactions are numbered 1-5. PROCESS: GLYCOLYSIS ATP reac HOCH₂ М OH H Н glucose H Но -O H OH OH 2P Localon ne T 2 NAD P OCH H 6 Но ADP. 2 NADH H OH H + 0 H OH Н 2 POC=0 HCOH I H₂CO P which com Н OH P OCH, 2 ADP H OT О Н НО Но 2 АТР Н H.COH C=O ATP 2011 Pearson Education, Inc This figure depicts the energy payoff phase of glycolysis. Reactions are numbered 6-10. HCOH H₂CO P you isomie 12000 OH POCH₂ H ADP . НО О Н НО H H 2 H₂CO P О О C=O HCO P H₂COH OH (4 POCH, H, OOH CO H c=0 HCOM . H₂CO P О c=0 CO P 11 CH₂ 2 ADP -- 10 nge? 6. Which enzyme (1-10) catalyzes the reaction that gives glycolysis its name? 2 0 0 НИЕ 0=0 CH₂ pyruvate 2 ATP 4. For each glucose molecule catabolized, what are the total or gross products at the end of the glycolysis? 5. What are the NET products of the entire glycolysis pathway from each glucose molecule fully catabolized?The enzyme is considered to be alan * ÇOO ÇOO Lactate dehydrogenase HO-C-H+ NAD C=0 + NADH + H CH: Pyruvate Lactate O Oxydoreductase O Isomerase O Hydrolase O Ligase O DehydrataseDraw OUT THE arrow pushing reaction mechanism for the following steps of glycolysis: SHOW/IDENTIFY the arrow pushing mechanism in at least 2 steps. CH,OPO CH,OH hexokinase 2+ H H H H H H ОН + ATP OH H ADP + H+ H ОН + НО HO OH H ОН H ОН Glucose-6-phosphate (G6P) Glucose