Under normal conditions, the human adrenal medulla secretes epinephrine (C₂H₁NO3) at a rate sufficient to maintain a concentration of 10-10 M in circulating blood. To appreciate what that concentration means, calculate the volume of water that you would need to dissolve 1.0 g (about 1 teaspoon) of epinephrine to a concentration equal to that in blood.
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- Creatinine, C4H7N3O, is a by-product of muscle metabolism, and creatinine levels in the body are known to be a fairly reliable indicator of kidney function. The normal level of creatinine in the blood for adults is approximately 1.0 mg per deciliter (dL) of blood. If the density of blood is 1.025 g/mL, calculate the molarity of a normal creatinine level in a 10.0 mL blood sample.Gout is caused by an error in metabolism that leads to abuildup of uric acid in body fluids, which is deposited as slightlysoluble sodium urate (C₅H₃N₄O₃Na) in the joints. If the extra-cellular [Na⁺] is 0.15 Mand the solubility of sodium urate is0.085 g/100. mL, what is the minimum urate ion concentration(abbreviated [Ur⁻]) that will cause a deposit of sodium urate?The normal concentration of Ca2+ in blood is 5.0 mEq>L. How many milligrams of Ca2+ are in 1.00 L of blood?
- Convert the experimental glucose concentration provided in below from mM (millimolar) to g/100 mL. Glucose Concentration is in mM 1.927 mM. ● Take the 1/100 dilution factor into consideration ● M will open the doors for you to get to g. ● Once at M assume 1L of solution. (Hint: this will help you when converting from M to moles) ● You will also need to calculate the molar mass of glucose which has the formula C6H12O6Pharmaceuticals When a medicine is administered orally, the concentration of the drug in the patient's circulation after t minutes is given by C(t) = 0.06t – 0.00021, where Osls 240 and the concentration is measured in mg/L. When does the highest serum concentration occur, and what is that maximum serum concentration?Calculate the concentration of an EDTA solution of which 24.22 mL were needed to titrate the Ca2+ions present in a 50.00 mL solution containing 246.7 mg CaCO3. Express your answer in terms of (a) molar concentration of EDTA (b) Ca Titer (mg Ca per mL of EDTA) MM Ca= 40.078 solve it in a way that it is in one equation already and cancelling all the values just like given in th epicture
- What is the concentration of B expressed in terms of A if the Kd is 33.0 uM, and the concentration of AB is 56.0 uM? A + B AB OB= 1850/A OB= 23 - A OB=23+ A OB= 0.589/AEnalaprilat is a competitive inhibitor of the angiotensin-converting enzyme (ACEACE), which cleaves the blood-pressure regulating peptide angiotensin I. ACEACE has a KM=52KM=52 μMμM for angiotensin I, which is present in plasma at a concentration of 75 μMμM. When enalaprilat is present at 2.4 nMnM, the activity of ACE in plasma is 14 %% of its uninhibited activity. What is the value of KIKI for enalaprilat?Blood pH is maintained at a range of 7.4. The following set of equations representsthe reactions of the blood buffering system. The pk, for the dissociation ofH,COg into HOg and H* is 6.3.Carbonic AnhydraseCO2 + H2OH2CO3> HCO3- + H+(a) (Calculate the ratio [HCO3 ]/[H,COg] at physiological pH. Show work.(b)) An individual with diabetes presented at an urgent care with fatigue andnausea. Lab tests showed that their blood [HOg ]/[H,COg] ratio was 3.4. Whatwas the pH of the patient's blood? Show work.(c) ) Clinic staff also noticed that the patient was breathing rapidly. What isthe reason for this rapid breathing and how might it help alleviate the patient'scondition?
- If we were handed a tuke of 2mg/mL BSA how much is required 20μL of each of the following Concentrations? to make zoul total bring up to volume with dH ₂0 @ 01125 mg/mL (1) 0,150 mg Ⓒ 0.50 mg/mL @ 0.75 mg/mL Ⓒ 1.0mg/ml /ML Can it be solved using C₂ C₁V₁ = C₂ V₂ If CI= V₁ yes, please show work. VzIf normal plasma pH is 7.4 and normal [CO2) is 1.2 mM, what is the normal (HCO321? The pK9 for this system is 6.1. Phosphoric acid (H3PO4) has three dissociable protons, with the pK,'s shown below. Which form of phosphoric acid predominates in a solution at pH 4? Explain your answer. Acid H3POA 2.14 H2PO4 6.86 HPO,2- 12.4Michael (4 year old; 19 kg) has been admitted to hospital due to a paracetamol overdose. The antidote for a paracetamol overdose is acetycysteine at a dose of 50 mg/kg. The ampoules contain 2 g in 10 mL. The acetycysteine is infused over 4 hours in 500 mL of 5% dextrose. Calculate the volume (in mLs to 1 d.p.) of acetylcysteine to be drawn from the ampoules for the infusion.
