Translation in eukaryotes and prokaryotes are similar and yet different. From a therapeutic perspective, why is this advantageous?
Q: Calculate the energy produced (in ATP molecules) achieved by complete oxidation of the hydrolysis…
A: Glycolysis involves the oxidation of mannose into pyruvate. Mannose enters glycolysis as…
Q: What type of glycosidic bond does the shown disaccharide have? HỌ CH,OH O CH,OHO Но. OH Но. OH
A: The above given disaccharide represents the structure of lactose. Lactose is made up of one molecule…
Q: What is the principle of dialysis? A. Highly soluble contaminants will be removed as the…
A: The removal of contaminants from a protein sample is important in the purification of proteins.
Q: Why do alcohol and water separate in DNA extraction process?
A: DNA extraction is defined as a process that is used widely for carrying out the purification fo DNA.…
Q: Some enzymes require additional ...........................to catalyze reactions effectively. These…
A: Introduction: Enzymes are large biological molecules important for thousands of metabolic processes…
Q: malate dehydrogenase is interconverted into isozymic forms by oxidizing and reducing agents
A: Malate dehydrogenase is found in a variety of organs in vertebrates. It has been discovered that…
Q: gene therapy in humans and other animals, the types of gene therapy, the methods used, and the…
A: Gene therapy is a medical approach to treat disease including cancer , genetic , or infectious…
Q: Is taking Multivitamins plus zinc every day affect Our lipid metabolism? If yes, in what way?
A: Zinc, alone or in conjunction with some other recognised antioxidant minerals and vitamins, may…
Q: Draw the Haworth Projection or the cyclic structure of the following:
A: organic compound organized in the form of aldehydes or ketones with multiple hydroxyl groups coming…
Q: In an individual with chronic and excessive alcohol intake, gluconeogenesis is often not favored…
A: Gluconeogenesis is the process of synthesis of glucose molecules from non-carbohydrate sources such…
Q: Trace the pathway of a protein from translation to the plasma membrane. You may name this protein…
A: Membrane proteins are a part of membrane structure, which are very important for a cell to carry out…
Q: Describe the effects of (1) oligomycin and (2) uncouplers of oxidative phosphorylation, e.g.,…
A: There are four electron transport chain complexes present in the inner mitochondrial membrane. These…
Q: A patient is prescribed 15mmol of potassium chloride injection. The ampoule contains 20mmol in 10ml.…
A: Given data A 10 ml ampule contains = 20 mmol
Q: Why marathon runners eat a meal rich in carbohydrates the day before the race
A: Nutrients are molecules that aids in the growth and development of living organisms. Nutrients are…
Q: explains the absorption of the GLEEVEC detailed
A: Introduction: Gleevec also known as imatinib mesylate is a kinase inhibitor that inhibits protein…
Q: TRUE OR FALSE: a) DNA replication requires the participation of at least 8 nucleoside…
A: The flow of genetic information from DNA to RNA, RNA to protein synthesis is called central dogma.…
Q: E. How many nucleotides would be required to generate a polypeptide that is 15 amino acids long?…
A: The genetic code is a sequence of three-letter combinations of nucleotides called codons, each…
Q: Benefits of a project "Drinking Water Refilling Station " to individuals and families and community…
A: Refilling stations for water bottles are now one of the most popular methods of decrease the…
Q: + H2O NH + HCO,- NH, Urea a. =NH HN =NH HN H2O + HCO,- H2N `CO, H,N b. L-Histidine L-Histamine c.…
A: Hi. Thank you for the question, As per the honor code, we are allowed to answer three sub-parts at a…
Q: Scenario IV. Electron Transport Chain Total Number of ATP Obtained from one Pyruvate Molecule Number…
A: Glucose or carbohydrates or sugars are oxidized through the process of glycolysis. Glycolysis occurs…
Q: In Zak-Henley's method in Determination of Total Serum Cholesterol, determine role of the sulfuric…
A: Cholesterol is a type of steroid. The normal serum cholesterol is 125-200mg/dL. Elevated serum…
Q: Using the data in this table, what is the AG° (in KJ/mol) for the reduction of FAD by water
A: The change in free energy is indicative of whether a reaction is spontaneous or not. If a reaction…
Q: How many hydrogen bonds exist between this DNA strand and its complementary strand? 5 -TGTCCCA-3'…
A: Nucleic acids are the biomolecules composed of nucleotide units. A nucleotide unit is composed of a…
Q: Write a possible mRNA base sequence that would lead to the production of this pentapeptide. (There…
A: mRNA is the abbreviation for messenger RNA, a type of single-stranded RNA involved in protein…
Q: How many ATP and NADH molecules would be produced during the citric acid cycle if 3 molecules of…
A: Cells are the basic unit of life. Cells derive energy from the metabolism of biomolecules such as…
Q: Describe the morphology and identification of Group A Streptococcus
A: Streptococci are microscopically bacterial coccoid cells, as well as a Gram-positive color when Gram…
Q: What are the two types of polysaccharides that are made up of starch?
A: Polysaccharide which is a type of carbohydrate contains long chain of polymeric carbohydrate which…
Q: Please answer both questions (a and b). Benzodiazepines such as diazepam and clonazepam act on…
A: Benzodiazepines are class of psychoactive drugs whose core chemical structure is the fusion of a…
Q: Hydrophobic signals after binding to the cell-surface receptors activate downstream signal…
A: Introduction: Cells do not work independently but continuously communicate with each other by…
Q: Increased protein metabolism leads to increase in which of the following? Select all that apply.…
A: Proteins are made up of amino acids. Protein metabolism involves the breakdown of proteins by…
Q: 10 b. How many different proteins composed of 100 amino acids could possibly exist?
A: The building blocks for the synthesis of proteins are amino acids. 20 different amino acids…
Q: Given the knowledge of biochemistry, make a sample outline of a new 24-hour healthy meal. Provide…
A: The human body can be viewed as an engine that releases the energy contained in the foods it…
Q: 3. Compute for the amount of each component of KCN broth if you were to prepare 280 ml. Express your…
A: KCN, potassium Cyanide Broth base is particularly used to differentiate the members of…
Q: Trypsin cleaves a polypeptide backbone at the C-terminal side of Arg or Lys residues, whereas…
A: Proteins are composed of amino acids, which are bound together by peptide linkage. Amino acids…
Q: The reaction is reversible. Check all that apply. acetyl CoA lactate ethanol
A: “Since you have asked multiple questions, we will solve the first question for you. If you want any…
Q: What is the maximum number of possible intra-peptide disulfide bonds for any given peptide form?
A: The side chains of Cysteine residues in proteins undergo oxidation to form disulfide linkages.
Q: Complete the table below regarding the different laboratory tests done for Carbohydrates. Only for…
A: There are different types of tests to check the presence of carbohydrates in different chemical…
Q: 7. Calculate the standard reduction potential and the standard free-energy change for each of the…
A: The Value of Standard reduction potential and the change in it's Gibb's free energy can determine…
Q: 87) For a the viral proteins a. If the viral protein is made in the RER, it will go back to the…
A: Proteins are composed of amino acids, which are bound together by peptide linkage. Amino acids…
Q: Consider a protein that is composed of two different polypeptide chains held together by several…
A: Proteins are composed of a linear chain of amino acids attached together via peptide bonds. Twenty…
Q: The hydrolysis of a substrate, S, by an enzyme has been studied in the lab. The following initial…
A: Consider the reaction where a substrate 'S' is converted to its product 'P' by an enzyme. The rate…
Q: explain Role of telomere in disease give a diagram
A: A telomere is a region at the ends of linear chromosomes that contains repeating nucleotide…
Q: According to the Arrenhius theory, an acid is: a. a substance that forms hydroxide ions b. a…
A: Arrhenius theory gives us the concept of acid and base. This theory is given based on the…
Q: Select all the true statements about sequential versus concerted models of allostery. Group of…
A: Allostery is a property of biological molecules of transmission of the effect of binding from one…
Q: (a) What is the function of helicase in DNA replication? (b) What is the function of DNA polymerase?…
A: DNA is called deoxyribonucleic acid. DNA act as genetic material in most organisms. DNA replication…
Q: Base your answers on the choices below: Specific Analyte for Test Mechanism of Test Positive Result…
A: The qualitative tests are used to detect the presence or absence of a substance. Different…
Q: what is the Cartagena protocol and how do the articles of the Cartagena protocol regulate the…
A: Cartagena protocol is an international agreement on Biosafety and as a supplement to convention on…
Q: In Zak-Henley's method in Determination of Total Serum Cholesterol, describe the role of Kiliani's…
A: Zak-Henley method is used for the determination of total serum cholesterol levels. Kiliani reagent…
Q: In sickle cell anemia, an inherited form of anemia in which the hemoglobin distorts the red blood…
A: The mutation that alters the codon that codes for a specific amino acid is called missense mutation.…
Q: Complete table 2. * Since you were not able to conduct an actual experiment on these tests, kindly…
A: Bromine test is a qualitative analysis of organic chemistry to detect unsaturation, anilines and…
Step by step
Solved in 3 steps
- Why are structural analogs of sugar molecules (such as Oseltamivir and zanamivir) effective in treatment of influenza-virus infection?Match the following antibiotics with the drug strategy that would provide resistance to them. rifampin which blocks transcription [ Choose ] Choose] tetracycline which misaligns the beta-lactamase anticodon to its codon mutation of the TRNA binding site of the ribosome penicillin which blocks peptidoglycan creation of alternate metabolic pathway that ultimately leads to the same product synthesis mutation of RNA polymerase polymyxin which causes leakage in the porin which removes drug from periplasmic space cell membrane sulfonamide which inhibits enzyme of [Choose ] folic acid synthesis pathway Question 14 2 pts % & 5 7Antibiotics that target bacterial molecules not previously exploited are desperately needed. One such target is the protein FtsZ. The small molecule 3-methoxybenzamide (3-MBA) is known to inhibit FtsZ in Bacillus subtilis but is not bacteriocidal. Nonetheless, researchers reasoned that 3-MBA offered a good starting point for the synthesis of a molecule that might be a potential drug candidate. Over 500 3-MBA analogues were synthesized and screened; one called PA190723 was extremely potent in its capacity to bind FtsZ and inhibit bacterial growth. In fact, when used in a mouse model, PA190723 was bacteriocidal against methicillinand multidrug-resistant Staphylococcus aureus. What makes FtsZ a good drug target? What preliminary information about 3-MBA would be helpful if you were designing the 3-MBA analogues? As these researchers move forward with clinical (human) testing, what other parameters and outcomes must be assessed besides the bacteriocidal activity of PA190723?
- Why is it better for a drug to be microbicidal than microbistatic?Aeroderma pigmentosum patients have a 10,000-fold increase in the risk of developing Skin cancer. These patients have to avoid exposure to UV light. Please explain why. To answer the question please: I) name the process that is affected and provide a scheme; 2) indicate template, substrates, sources of energy that are involved in the process; 3) propose the consequences of the process.1. a)how is it possible for such drugs to selectively kill bacterial cells and not our own cells? b)Provide an example of post-translational regulation of protein activity and explain the advantage of regulating each protein/process at the post-translational level instead of the transcriptional level.
- The ribosome is the target for many important antibiotics. These drugs must discriminate between bacterial and eukaryotic ribosomes to achieve drug specificity and toxicity. For the two common antibiotics below, what is their mechanism of action and why are they more toxic to bacteria than eukaryotes? a) Tetracycline b) ErythromycinVarious antimicrobial drugs to treat microbial infection have diverse mechanism of action. Consider the following antimicrobial drugs: A. Seconeolitsine, known as DNA topoisomerase I inhibitor in bacteria. (i) Explain briefly how inhibiting DNA topoisomerase I is a good mechanism of action for an antibiotic, include possible molecular machineries being targeted. (ii) What would be an appropriate response if seconeolitsine works well by stating the state of supercoiling in bacteria. (iii) To prove your answer (ii), you test the condition of bacterial DNA by running gel electrophoresis, one has been treated with seconeolitsine (+ sample) and the other one is not (- sample). Explain the position of each + sample and – sample band on the gel in reference to the point of origin (where you load your samples) or how far each DNA sample travel across agarose gel. (iv) Explain why you would expect answer (iii) for each + sample and – sample. B.…Resistance to many penicillins is the result of cell wall mutations in a variety of bacteria. True or false?
- In the: A mutated TBP protein Explain: (a) What is the process affected? (b) What is the Effect on the process? (c) Does it affect prokaryotes, eukaryotes or both?Which of the following would be a good chemotherapy approach: blocking formationof the ribonucleotide GTP or blocking formation of the deoxyribonucleotide dGTP?Why? Please explain the chemical differences between each of the two nucleotides. Use the specific processes below to support your choice by explaining how either GTP or dGTPare related to these and how loss of the particular molecule would affect each process. *PEP carboxykinase in gluconeogenesis*Succinyl-CoA synthetase in the TCA Cycle*Glucagon signal transductionDraw the mechanism of action of an HIV protease. Label the substrate, the intermediates, and the products. Indicate each type of catalysis that occurs throughout the mechanism..