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- All of the following are filamentous proteins EXCEPTTissue injury can result in either regeneration or healing. Explain the similarities and differences between these responses, highlighting the significance of the Extracellular MatrixMatch the following to their proper description (answers may be used more than once). Gap junctions Adhering junctions Desmosomes Hemidesmosomes Tight junctions Tight junctions Tight junctions Connexons Connexons Zonulae adherens Cadherins Desmosomes Are also known as “zonulae adherens”. Are also known as “zonulae occludens”. Are calcium ion-dependent glycoproteins that mediate adhesion in adhering junctions. Are hexameric complexes formed by connexin proteins. Bind the cells to the basal lamina. Contain a central hydrophilic pore and occur in gap junctions. Contain protein filaments. Encircle the cell and provide firm connections with neighboring cells. Form seals that prevent the flow materials between adjacent epithelial cells. Form thin bands that completely encircle the cell. Permit the rapid exchange of materials between adjacent cells. Provide firm adhesion between cells via protein filaments that are coupled to intracellular filaments via a protein plaques.
- Which of the following membrane lipids is mainly structural? Phosphatidylthanolamine All of the other answers are correct Phosphatidylcholine Spingomyelin Inositol phospholipidsA 5-year-old child is admitted to the hospital having experienced repeated fractures over the preceding three years, predominantly due to overexertion. On examination, the patient's sclera appears blue; his teeth are bell shaped and show discoloration. X-ray reveals spine abnormalities and poor bone mineralisation. Which of the following extracellular matrix components is most likely to be affected in this child? Answers A - E A Collagen type I B Collagen type II C Collagen type VII D Glycoprotein E Osteocalcin O O OMembrane proteins with specialized functions and distinct from other membrane proteins may be localized in one area of the cell membrane. True False
- Which of the followings is not a possible component of extracellular matrix? (LO-K8) Collagen Tubulin Glycosaminoglycans ElastinDiscuss about Intercellular and intracellular interactions ofclassical cadherins in typical adherens junctions.What process best characterizes Ca2+ movement from the cytosol (low Ca2+ concentration) into the endoplasmic reticulum (high Ca2+ concentration)? O Calcium movement is spontaneous O Calcium movement involves active transport O Calcium movement occurs by facilitated diffusion using a transporter protein O Calcium movement does not require energy O Calcium movement occurs by passive diffusion A
- Facilitated diffusion is a lipid-mediated process. true falseGab junctions are intracellular matrix thatX Membrane proteins are necessary for active transport Y Membrane proteins play a role in faciitated diffusion Select one Both statements are FALSE Both statements are TRUE Only the second statement is TRUE Only the fist statement is TRUE